Repetitive Transcranial Magnetic Stimulation Therapy in Spinal Cord Injury Related Neuropathic Pain
Efficacy of Repetitive Transcranial Magnetic Stimulation Therapy in Neuropathic Pain Associated With Spinal Cord Injury; Randomized Controlled Trial
Afyonkarahisar Health Sciences University
63 participants
Dec 16, 2024
INTERVENTIONAL
Conditions
Summary
The aim of our study is to investigate the effect of different protocols of high-frequency Repetitive Transcranial Magnetic Stimulation (rTMS) therapy added to the rehabilitation program on neuropathic pain,depression, quality of life and quality of sleep compared to each other and placebo group in participants with spinal cord injury.
Eligibility
Inclusion Criteria1
- Aged 18-75 years Physician-diagnosed spinal cord injury for at least 3-months Neuropathic pain for at least 3-months Pain not attributable to any other conditions
Exclusion Criteria16
- Having an important comorbid disease such as severe heart disease (aortic stenosis, angina, hypertrophic cardiomyopathy, uncontrolled hypertension,arrhythmia, pacemaker)
- Neurodegenerative disease
- Epilepsy
- History of antiepileptic drug use
- Cognitive dysfunction
- Lower extremity peripheral nerve injury
- Increased intracranial pressure or uncontrolled migraine
- Infection on the skin in the application area.
- Having a brain lesion or a history of drug use that will affect the seizure threshold.
- Any TMS-related contraindications, for example:
- Pacemaker
- Metallic implant
- Previous seizure
- Psychiatric disorders (excluding depression and anxiety)
- Malignancy
- Current pregnancy
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Interventions
It was planned to apply the dorsolateral prefrontal cortex daily for 20 sessions.Along with the daily rTMS session, participants will continue to use the medications in the medical treatment at the same effective dose and no dose changes will be made during the treatment.
It was planned to apply the M1 motor cortex daily for 20 sessions.Along with the daily rTMS session, participants will continue to use the medications in the medical treatment at the same effective dose and no dose changes will be made during the treatment.
It was planned to apply the daily for 20 sessions.Along with the daily rTMS session, participants will continue to use the medications in the medical treatment at the same effective dose and no dose changes will be made during the treatment.
Locations(1)
View Full Details on ClinicalTrials.gov
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NCT06726954