RecruitingNot ApplicableNCT06738394

Enhancing Physical Function in Older Adults With Chronic Kidney Disease

Enhancing Physical Function in Older Adults With Chronic Kidney Disease (EPIC): A Pilot Randomized Controlled Trial

Sponsor

Wake Forest University Health Sciences

Enrollment

30 participants

Start Date

Jul 31, 2025

Study Type

INTERVENTIONAL

Conditions

Chronic Kidney Diseases

Summary

The goal of this pilot randomized controlled trial is to examine the feasibility and safety of a 12-week high-velocity resistance training (HVRT) intervention in older adults with chronic kidney disease (CKD) stages 4-5 and to generate preliminary data to inform a future study investigating the efficacy of HVRT for improving muscle power and physical function. Researchers will compare HVRT to an attention control condition consisting of weekly group sessions covering topics on healthy lifestyle. This study seeks to: 1. Determine whether implementing an HVRT intervention is feasible and safe for mobility-limited older adults with advanced CKD. 2. Collect preliminary data on the efficacy of HVRT for improving muscle power and physical function in mobility-limited older adults with advanced CKD.

Eligibility

Min Age: 65 YearsMax Age: 100 Years

Plain Language Summary

Simplified for easier understanding

This study tests whether a structured exercise or physical activity program can improve physical function and quality of life in older adults with chronic kidney disease (CKD). Many people with CKD experience fatigue and reduced physical ability, and this trial aims to see if exercise can help. **You may be eligible if...** - You have chronic kidney disease at stage 3, 4, or 5 - You are physically able to do exercise - You live within 20 miles of Wake Forest University's Reynolda Campus - You are a fluent English speaker - You are willing to be randomly assigned to an exercise group **You may NOT be eligible if...** - You are currently on dialysis (hemodialysis or peritoneal dialysis) or are expected to start dialysis in the next 6 months - You plan to travel away from the area for an extended period during the study - You have health conditions that prevent safe exercise participation Talk to your doctor to see if this trial is right for you.

This summary was AI-generated to explain the trial in plain language. It is not medical advice. Always discuss eligibility with your doctor before enrolling in a clinical trial.

Interested in this trial?

Get notified about updates and connect with the research team.

Interventions

BEHAVIORALHigh-Velocity Resistance Training

High-velocity resistance training for patients with non-dialysis dependent chronic kidney disease Stages 3-5 with mobility limitations.

BEHAVIORALAttention

Dedicated contact, information, and motivation throughout the course of the study via weekly group sessions and informational handouts.

Locations(1)

Wake Forest University Health Sciences

Winston-Salem, North Carolina, United States

View Full Details on ClinicalTrials.gov

For the most up-to-date information, visit the official listing.

Visit

NCT06738394

Related Trials

Precision Medicine Approaches to Renal Osteodystrophy

NCT058809141 location

Safety and Tolerability of Difelikefalin in Adolescents on Haemodialysis With Moderate-to-Severe Pruritus

NCT0659339216 locations

Theory-based Health Behaviour Change Intervention in Patients of Metabolic Syndrome With Chronic Kidney Disease

NCT065277681 location

Theory-based Health Behaviour Change Intervention in Individuals of Metabolic Syndrome With Chronic Kidney Disease

NCT067157351 location

Impact of Trans-catheter Aortic Valve Implantation on Renal Function

NCT076267101 location