RecruitingNot ApplicableNCT06750692

Comparison of the Effects of Mirror Therapy,rTMS and Robotic-assisted Hand Therapy in Stroke Patients

Comparison of the Effects of Mirror Therapy,Repetitive Transcranial Magnetic Stimulation and Robotic-assisted Hand Therapy Added to Neurological Rehabilitation on Upper Extremity Functions, Quality of Life and Pain in Stroke Patients


Sponsor

Afyonkarahisar Health Sciences University

Enrollment

120 participants

Start Date

Dec 27, 2024

Study Type

INTERVENTIONAL

Conditions

Summary

The aim of the study is to investigate the comparison of the effects of mirror therapy, Repetitive Transcranial Magnetic Stimulation and robot-assisted hand therapy added to conventional neurological rehabilitation on upper extremity function, quality of life and pain in stroke.


Eligibility

Min Age: 40 YearsMax Age: 80 Years

Inclusion Criteria5

  • Female and male patients between the ages of 40-80
  • stroke at least 3 months ago
  • voluntarily agreed to participate in the study regularly, whose health status is suitable for rehabilitation and who are medically stable
  • mini mental test score of 15 and above
  • Neurologically stable patient

Exclusion Criteria19

  • significant comorbidities such as serious heart disease (aortic stenosis, angina, hypertrophic cardiomyopathy, arrhythmia, pacemaker) and uncontrolled hypertension
  • history of epilepsy, antiepileptic drug use
  • intracranial metal objects
  • intraauricular implants
  • cognitive dysfunction
  • upper extremity peripheral nerve injuries
  • malignancy
  • active infection
  • skin infections or open wounds in the application area
  • inflammatory diseases
  • orthopedic injuries that may limit maximum effort capacity
  • brain lesion or drug use history that may affect the seizure threshold
  • increased intracranial pressure
  • uncontrolled migraine
  • severe spasticity in the hand (MAS≥3)
  • contracture in the hand
  • have had a fracture or surgery on the hemiplegic side in the last 6 months
  • severe visual impairment
  • severe depression

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Interventions

OTHERProcedure: Mirror therapy

The first group of participants will receive a total of 20 sessions of upper extremity mirror therapy program, 5 sessions per week for 4 weeks.

DEVICEDevice: Low Frequency rTMS Protocol

Repetitive Transcranial Magnetic Stimulation (rTMS) will be applied at an intensity of 100-110% of the resting motor threshold and low frequency (1 Hz) to the contralateral M1 upper extremity motor cortex region for a total of 20 sessions, 5 sessions per week for 4 weeks. rTMS application is planned to provide magnetic stimulation with the stimulator of the Magventure MagPro R30 device.

DEVICERobotic-assisted hand therapy

In the Robot Assisted Therapy group, a total of 20 sessions will be applied 5 days a week for 4 weeks using continuous passive range of motion, active assistive exercise and play therapy programs for hemiplegic upper extremities with AMADEO (Tyromotion Austria).


Locations(1)

Afyonkarahisar Health Sciences University

Afyonkarahisar, Turkey (Türkiye)

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NCT06750692


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