RecruitingNCT06781450

Study in Patients With Relapsed/Refractory Primary Mediastinal Lymphoma Treated With Pembrolizumab or Nivolumab in Combination With Brentuximab Vedotin in a Real-life Context

Retrospective Observational Study in Patients With Relapsed / Refractory Primary Mediastinal Lymphoma Treated With Pembrolizumab or Nivolumab in Combination With Brentuximab Vedotin in a Real-life Context


Sponsor

IRCCS Azienda Ospedaliero-Universitaria di Bologna

Enrollment

50 participants

Start Date

Apr 23, 2022

Study Type

OBSERVATIONAL

Conditions

Summary

Observational, Non-Interventional, Retrospective, Multicenter Study Focusing on the Efficacy and Safety of Pembrolizumab Monotherapy and Nivolumab in Combination With Brentuximab Vedotin in Clinical Practice Patients With Primary Mediastinal B Cell Lymphoma Relapsed/Refractory


Eligibility

Min Age: 18 Years

Plain Language Summary

Simplified for easier understanding

This study is reviewing real-world outcomes of patients with relapsed or treatment-resistant primary mediastinal B-cell lymphoma (a type of chest lymphoma) who were treated with checkpoint inhibitor drugs like pembrolizumab (alone) or nivolumab combined with brentuximab vedotin. **You may be eligible if...** - You are 18 or older - You have relapsed or refractory primary mediastinal B-cell lymphoma - You received pembrolizumab alone or nivolumab plus brentuximab vedotin as part of routine clinical care (not in a clinical trial) - Your treatment ended before November 2021 **You may NOT be eligible if...** - You received these drugs as part of a clinical trial (not routine care) Talk to your doctor to see if this trial is right for you.

This summary was AI-generated to explain the trial in plain language. It is not medical advice. Always discuss eligibility with your doctor before enrolling in a clinical trial.

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Locations(3)

IRCCS Azienda Ospedaliero - Universitaria di Bologna

Bologna, Bologna, Italy

Azienda Ospedaliera Universitaria- POLICLINICO BARI

Bari, Italy

Fondazione IRCCS Istituto Nazionale dei Tumori

Milan, Italy

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NCT06781450


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