RecruitingNot ApplicableNCT06786572

Interoceptive Training Enhanced Mindfulness

Interoceptive Training Enhanced Mindfulness (ITEM): Acceptability and Measurement


Sponsor

Veterans Medical Research Foundation

Enrollment

48 participants

Start Date

Sep 10, 2025

Study Type

INTERVENTIONAL

Conditions

Summary

This pilot randomized controlled trial will compare a novel mindfulness training to interoceptive exposure to establish feasibility and acceptability as an intervention for anxiety sensitivity.


Eligibility

Min Age: 18 Years

Inclusion Criteria5

  • Veteran status
  • able to read and speak English
  • ASI-3 score of 23 or higher
  • clinically meaningful distress/impairment related to an emotional or somatic complaint as determined by a Clinical Global Impression Scale (CGI) of 3 or greater
  • Internet access via a device that can support remote study activities and ability to attend in person appointments

Exclusion Criteria5

  • serious mental illness, including bipolar disorder or psychotic illness
  • current, untreated alcohol or substance use disorder
  • moderate-severe suicidality that would likely result in the need for urgent intervention in the next 2 months
  • current regular meditation practice or treatment for AS-related condition
  • cognitive dysfunction that interferes with the ability to engage in treatment

Interventions

OTHERMindfulness training

Brief mindfulness training focused on management of unwanted internal sensations

BEHAVIORALInteroceptive exposure

Cognitive behavioral therapy focused in interoceptive exposure to unwanted internal sensations


Locations(1)

VA San Diego Healthcare System

San Diego, California, United States

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NCT06786572