Hybrid Intelligence for Trustable Diagnosis and Patient Management of Prostate Cancer (HIT-PIRADS)

This study is using artificial intelligence tools to improve the accuracy of prostate cancer diagnosis by combining MRI imaging, PSA blood tests, and other clinical data — with the goal of reducing unnecessary biopsies. **You may be eligible if...** - You are a male between 18 and 89 years old - Your PSA (a blood test for prostate health) is between 2 and 10 ng/mL, or slightly elevated with an abnormal rectal exam - You have never had a prostate biopsy before - You have a life expectancy of at least 10 years - You are generally healthy enough to function normally (ECOG performance status 0–2) **You may NOT be eligible if...** - You have taken a 5-alpha reductase inhibitor medication (like finasteride or dutasteride) within the past 12 months - You had a prostate infection in the past month - You have previously been treated for prostate cancer - You had a urological procedure in the past month - You have a contraindication to MRI scanning Talk to your doctor to see if this trial is right for you.