RecruitingPhase 3NCT06842199

Efficacy, Safety, Pharmacokinetics of ICP-488 in Patients With Moderate to Severe Plaque Psoriasis

A Multicenter, Randomized, Double-blind, Placebo-controlled Phase III Study to Evaluate the Efficacy and Safety of Oral ICP-488 in Patients With Moderate to Severe Plaque Psoriasis

Sponsor

Beijing InnoCare Pharma Tech Co., Ltd.

Enrollment

383 participants

Start Date

Mar 20, 2025

Study Type

INTERVENTIONAL

Conditions

Plaque Psoriasis Patients

Summary

This is a multicenter, randomized, double-blind, placebo-controlled Phase III clinical study to evaluate the efficacy, safety, PK characteristics of ICP-488 in Chinese adults with moderate to severe plaque psoriasis.

Eligibility

Min Age: 18 YearsMax Age: 75 Years

Plain Language Summary

Simplified for easier understanding

This clinical trial is studying a drug called ICP-488 Placebo and a drug called ICP-488 Tablets for people with plaque psoriasis patients. The study is currently recruiting participants at 46 locations. People eligible for this study include aged 18 Years to 75 Years.

This summary was AI-generated to explain the trial in plain language. It is not medical advice. Always discuss eligibility with your doctor before enrolling in a clinical trial.

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Interventions

DRUGICP-488 Tablets

Eligible patients will receive ICP-488 orally as per the protocol

DRUGICP-488 Placebo

Eligible patients will receive ICP-488 Placebo orally as per the protocol

Locations(46)

The First Affiliated Hospital of Anhui Medical University

Hefei, Anhui, China

The Second Affiliated Hospital of Wannan Medical College

Wuhu, Anhui, China

Beijing Chao-Yang Hospital，Capital Medical University

Beijing, Beijing Municipality, China

Beijing Friendship Hospital, Capital Medical University

Beijing, Beijing Municipality, China

Peking University Third Hospital

Beijing, Beijing Municipality, China

Beijing Tongren Hospital,CMU

Beijing, Beijing Municipality, China

The First Affiliated Hospital of Chongqing Medical University

Chongqing, Chongqing Municipality, China

Chongqing Traditional Chinese Medicine Hospital

Chongqing, Chongqing Municipality, China

Fujian Medical University Union Hospital

Fuzhou, Fujian, China

The First Affiliated Hospital of Fujian Medical University

Fuzhou, Fujian, China

Dermatology Hospital of Southern Medical University

Guangzhou, Guangdong, China

Sun Yat-sen Memorial Hospital, Sun Yat-sen University

Guangzhou, Guangdong, China

Liuzhou People's Hospital

Liuzhou, Guangxi, China

The Affiliated Hospital of Guizhou Medical University

Guiyang, Guizhou, China

Affiliated Hospital of Chengde Medical University

Chengde, Hebei, China

The Second Hospital of Hebei Medical University

Shijiazhuang, Hebei, China

The 2nd Affiliated Hospital of Harbin Medical University

Harbin, Heilongjiang, China

The Second Affiliated Hospital of Henan University of Science and technology

Luoyang, Henan, China

Nanyang Central Hospital

Nanyang, Henan, China

Sanmenxia Central Hospital

Sanmenxia, Henan, China

Henan Provincial People's Hospital

Zhengzhou, Henan, China

Jingzhou Central Hospital

Jingzhou, Hubei, China

Wuhan Hospital Of Traditional Chinese and Western Medicine (Wuhan No.1 Hospital)

Wuhan, Hubei, China

Xiangya Hospital of Central South University

Changsha, Hunan, China

The Second Xiangya Hospital of Central South

Changsha, Hunan, China

The First People's Hospital of Changzhou

Changzhou, Jiangsu, China

The First People's Hospital of Lianyungang

Lianyungang, Jiangsu, China

Hospital for skin diseases,Institute of dermatology chinese academy of medical sciences，peking union medical college

Nanjing, Jiangsu, China

First Affiliated Hospital of Gannan Medical University

Ganzhou, Jiangxi, China

Dermatology Hospital of Jiangxi Province

Nanchang, Jiangxi, China

The First Hospital of Jilin University

Changchun, Jilin, China

Northeast International Hospital

Shenyang, Liaoning, China

Qilu Hospital of Shandong University

Jinan, Shandong, China

Huashan Hospital, Fudan University

Shanghai, Shanghai Municipality, China

Shanghai Skin Disease Hospital skin Disease of tongji University

Shanghai, Shanghai Municipality, China

Taiyuan Central Hospital

Taiyuan, Shanxi, China

The First Affiliated Hospital of Xi'an Jiaotong University

Xi’an, Shanxi, China

The Second Affiliated Hospital of Xi'an Jiaotong University

Xi’an, Shanxi, China

Chengdu Second People's Hospital

Chengdu, Sichuan, China

Sichuan Provincial People's Hospital

Chengdu, Sichuan, China

Tianjin Academy of Traditional Chinese Medicine Affiliated Hospital

Tianjin, Tianjin Municipality, China

The First Affiliated Hospital of Kunming Medical University

Kunming, Yunnan, China

The Second Affiliated Hospital Zhejiang University School of Medicine

Hangzhou, Zhejiang, China

The Fourth Affiliated Hospital, Zhejiang University School of Medicine

Jinhua, Zhejiang, China

The First Affiliated Hospital Of Ningbo University

Ningbo, Zhejiang, China

The first Affiliated hospital of Wenzhou Medical University

Wenzhou, Zhejiang, China

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NCT06842199