RecruitingNCT06861868

Brain and Behavior Influences on Obesity Development From Infancy Through Childhood

Early Brain Development and Child Nutrition and Obesity


Sponsor

Johns Hopkins University

Enrollment

210 participants

Start Date

Dec 2, 2024

Study Type

OBSERVATIONAL

Conditions

Summary

The investigators project, RESONATE, aims to investigate why some children develop obesity. To do this it uses data on eating and eating-related behaviors, genetic and environmental factors, and brain structure and function. This data is collected in a sub-sample of RESONANCE, a large study of families of children from infancy through childhood. The results will lay foundations for the development of early interventions to prevent or treat obesity.


Eligibility

Min Age: 7 YearsMax Age: 12 Years

Inclusion Criteria1

  • Participants from the RESONANCE cohort are eligible if the participant will reach 7-12 years of age during the proposed project period and have no food allergies.

Exclusion Criteria6

  • In utero exposure to alcohol, cigarette, or illicit substances;
  • First trimester fetal US abnormalities;
  • Complicated pregnancy (e.g., pre-eclampsia);
  • Complicated delivery, including APGAR scores less than 8 and/or neonatal intensive care unit (NICU) admission;
  • History of neurological (e.g., epilepsy), psychiatric (e.g., anxiety or depression requiring treatment with medication) or developmental disorder (e.g., autism spectrum disorder (ASD), dyslexia);
  • Contraindications for MRI including metal in the body, claustrophobia.

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Locations(4)

Hugo W. Moser Research Institute at Kennedy Krieger, Inc.

Baltimore, Maryland, United States

Johns Hopkins University School of Medicine

Baltimore, Maryland, United States

Rhode Island Hospital

Providence, Rhode Island, United States

University of Washington

Seattle, Washington, United States

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NCT06861868


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