Motor Learning of Fall Resistant Skills Through Slip and Trip Exposure in Multiple Sclerosis
Georgia State University
64 participants
Jan 1, 2026
INTERVENTIONAL
Conditions
Summary
The primary purpose of this interventional study is to examine the overall motor learning capacity from exposure to repeated perturbations among ambulatory people with multiple sclerosis (MS). This project will advance our understanding of learning new motor skills from exposure to external perturbations. If it is proven that people with MS can learn motor skills from perturbation training, the findings from this study will pave a theoretical foundation for applying perturbation training as a promising fall prevention intervention for people with MS.
Eligibility
Inclusion Criteria7
- Clinically confirmed multiple sclerosis
- At least 45 years old
- Able to walk independently at least 25 feet
- Able to stand independently for at least 30 seconds
- Patient Determined Disability Steps score between 0 and 4
- Free from pregnancy
- Montreal Cognitive Assessment score of 23 or higher
Exclusion Criteria4
- Previous experience with perturbation training
- T-score from the dual x-ray absorptiometry (DXA) scan of less than -2.5
- Coexisting psychiatric disorders or other neurological conditions, severe medical illness, or cardiovascular diseases
- Participants have had a relapse in the past 8 weeks
Interventions
Unexpected slips blended with trips and unperturbed walking trials on a treadmill. A safety harness will be worn at all times.
Treadmill walking for the same amount of time as the training group without perturbation. A safety harness will be worn at all times.
Locations(1)
View Full Details on ClinicalTrials.gov
For the most up-to-date information, visit the official listing.
NCT06919900