RecruitingNot ApplicableNCT06919900

Motor Learning of Fall Resistant Skills Through Slip and Trip Exposure in Multiple Sclerosis


Sponsor

Georgia State University

Enrollment

64 participants

Start Date

Apr 6, 2026

Study Type

INTERVENTIONAL

Conditions

Summary

The primary purpose of this interventional study is to examine the overall motor learning capacity from exposure to repeated perturbations among ambulatory people with multiple sclerosis (MS). This project will advance our understanding of learning new motor skills from exposure to external perturbations. If it is proven that people with MS can learn motor skills from perturbation training, the findings from this study will pave a theoretical foundation for applying perturbation training as a promising fall prevention intervention for people with MS.


Eligibility

Min Age: 45 YearsMax Age: 89 Years

Plain Language Summary

Simplified for easier understanding

This study is testing whether exposing people with multiple sclerosis (MS) to controlled slips and trips in a safe environment can help them learn to recover their balance and reduce falls. Falling is a major risk for people with MS, and this training aims to build protective reflexes. **You may be eligible if...** - You have a confirmed diagnosis of multiple sclerosis - You are at least 45 years old - You can walk at least 25 feet on your own - You can stand independently for at least 30 seconds - Your disability level is mild to moderate (PDDS score 0–4) - You are not pregnant - Your memory and thinking are within normal range (MoCA score 23 or above) **You may NOT be eligible if...** - You have had prior balance perturbation training - You have significant bone density loss (T-score less than -2.5 on a bone scan) - You have a psychiatric disorder, other neurological condition, or serious heart disease - You had a relapse of MS in the past 8 weeks Talk to your doctor to see if this trial is right for you.

This summary was AI-generated to explain the trial in plain language. It is not medical advice. Always discuss eligibility with your doctor before enrolling in a clinical trial.

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Interventions

BEHAVIORALPerturbation Training

Unexpected slips blended with trips and unperturbed walking trials on a treadmill. A safety harness will be worn at all times.

BEHAVIORALTreadmill Walking

Treadmill walking for the same amount of time as the training group without perturbation. A safety harness will be worn at all times.


Locations(1)

Georgia State University Biomechanics Lab

Atlanta, Georgia, United States

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NCT06919900


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