RecruitingNCT06924021

Age-Related Macular Degeneration Benchmark Imaging Dataset (ABID)


Sponsor

University of Wisconsin, Madison

Enrollment

1,000 participants

Start Date

May 12, 2025

Study Type

OBSERVATIONAL

Conditions

Summary

1000 participants from up to 25 international locations who are at least 50 years old with either healthy eyes or a diagnosis of Age-Related Macular Degeneration (AMD) will be consented to provide images of their eyes for a new dataset. This dataset is an important step in developing an Artificial Intelligence (AI) based screening tool for AMD.


Eligibility

Min Age: 50 Years

Inclusion Criteria3

  • Participants greater than or equal to 50 years of age at time of signing Informed Consent Form
  • Willing to comply with all study procedures and sign the Informed Consent Form (ICF)
  • Individuals with normal healthy eyes or diagnosed with any stage of Age-Related Macular Degeneration (treatment naïve patients with early, intermediate, or late AMD). The diagnosis and eligibility review will be confirmed by Central Reading Center.

Exclusion Criteria7

  • Therapeutic treatment for any type of AMD, in either eye. Supplements, such as AREDS2 formula, are allowed.
  • Unable to acquire adequate quality images, as evaluated by the Central Reading Center
  • Severe vision loss requiring urgent surgery
  • Contraindicated for acquiring retinal images due to narrow anterior chamber angles or hypersensitivity to light
  • A systemic or ocular condition that in the opinion of the Investigator would preclude participation in the study
  • Unwilling to sign informed consent form
  • Currently or previously enrolled in an interventional AMD clinical trial

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Interventions

OTHERRetinal Imaging

Eligible participants will undergo one retinal imaging session of both eyes for the following: * Single field stereo color fundus photography (cFP) - pre and post dilation * Macular spectral domain-optical coherence tomography (SD-OCT)


Locations(14)

Bergstrom Eye Research LLC

Fargo, North Dakota, United States

Erie Retina Research

Erie, Pennsylvania, United States

Retina Foundation of the Southwest

Dallas, Texas, United States

Valley Retina Institute

McAllen, Texas, United States

Retina Consultants of Texas (Houston)

The Woodlands, Texas, United States

University of Utah - John A. Moran Eye Center

Salt Lake City, Utah, United States

University Station Eye Care Clinic

Madison, Wisconsin, United States

Charles Research Center

Buenos Aires, Argentina

Adelaide Eye and Retina Centre

Adelaide, Australia

Centre Hospialier Intercommunal de Paradis (Centre Monticelli Paradis)

Marseille, France

University of Bonn - Department of Ophthalmology

Bonn, Germany

Sankara Nethralaya, Medical Research Foundation

Chennai, Tamil Nadu, India

Aravind Eye Hospital

Chennai, Tamil Nadu, India

Aga Khan University

Karachi, Pakistan

View Full Details on ClinicalTrials.gov

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NCT06924021


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