RecruitingNCT06935422
Role of Cerebroplacental Ratio Discordance at 16-20 Weeks in Predicting Monochorionic Twin Pregnancies' Specific Complications
Role of Cerebroplacental Ratio Discordance at 16-20 Weeks in Predicting Monochorionic Twin Pregnancies' Specific Complications : a Prospective Cohort Study
Sponsor
Ain Shams Maternity Hospital
Enrollment
55 participants
Start Date
Mar 1, 2025
Study Type
OBSERVATIONAL
Conditions
Summary
The purpose of this study is to evaluate the predictive value of CPR discordance at 16-20 weeks in MCDA twin pregnancies in predicting monochorionic-specific complications such as TTTS, TAPS, sFGR and IUFD of one or both fetuses
Eligibility
Sex: FEMALE
Inclusion Criteria3
- Aged 18 years or more and able to consent.
- Monochorionic Diamniotic twin pregnancy.
- Discordant inter-twin cerebroplacental ratio at 16-20 weeks of gestation.
Exclusion Criteria5
- Fetal structural malformations or chromosomal abnormalities in any of the twins as detected by anomaly scan antenatally or neonatal examination postnatally (chromosomal abnormalities and some congenital malformations can interfere with normal fetal growth).
- Identified infectious etiologies detected during immediate postnatal examination or during pregnancy (fetal infections can cause FGR ,usually symmetric type particularly if they occur in early gestation).
- Referral after development of Twin to twin transfusion syndrome, twin anemia polycythemia sequence or selective fetal growth restriction.
- Single fetal demise at the time enrollment in the study.
- Conjoint twins.
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Interventions
DEVICEUltrasound
Measuring cerebroplacental ratio discordance in monochorionic twins at 16-20 Weeks of gestation
Locations(1)
View Full Details on ClinicalTrials.gov
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NCT06935422