RecruitingPhase 3NCT06953869

Evaluating the Effects of Tasimelteon vs. Placebo in Treating Pediatric Insomnia

A Multicenter, Double-Blind, Randomized Study to Evaluate the Effects of Tasimelteon vs. Placebo in Treating Pediatric Insomnia


Sponsor

Vanda Pharmaceuticals

Enrollment

420 participants

Start Date

Apr 21, 2025

Study Type

INTERVENTIONAL

Conditions

Summary

This is a multicenter, double-blind, randomized study to evaluate the efficacy and safety of a daily single oral dose of tasimelteon and matching placebo in male and female pediatric participants with insomnia disorder.


Eligibility

Min Age: 2 YearsMax Age: 17 Years

Inclusion Criteria4

  • Ability and acceptance to provide written informed consent of the participant or legal guardian (and assent as required).
  • Confirmed clinical diagnosis of insomnia disorder
  • Males and Females between 2 and 17 years, inclusive.
  • The sleep disturbance must not be a result of another medication.

Exclusion Criteria4

  • Inability to dose daily with tasimelteon or previous intolerance to tasimelteon.
  • Indication of impaired liver function.
  • Pregnant or lactating females.
  • A positive test for drugs of abuse.

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Interventions

DRUGTasimelteon Oral Suspension

Single daily dose, weight-based liquid suspension formulation.

DRUGPlacebo

Placebo comparator.


Locations(3)

Vanda Investigational Site

Winter Park, Florida, United States

Vanda Investigational Site

Charlotte, North Carolina, United States

Vanda Investigational Site

San Antonio, Texas, United States

View Full Details on ClinicalTrials.gov

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NCT06953869


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