RecruitingNot ApplicableNCT06998745

The Impact of MTM Model on the Efficacy and Safety of Anticoagulant Therapy in Postoperative Colorectal Cancer Patients


Sponsor

Sixth Affiliated Hospital, Sun Yat-sen University

Enrollment

327 participants

Start Date

May 1, 2025

Study Type

INTERVENTIONAL

Conditions

Summary

Anticoagulants are classified as high-risk medications, with their main adverse drug events (ADEs) being recurrent venous thromboembolism (VTE) and bleeding events.Postoperative colorectal cancer (CRC) patients exhibit a high probability of recurrent VTE and bleeding during anticoagulation therapy.The Medication Therapy Management (MTM) model will contribute to reducing ADEs associated with anticoagulants in CRC patients.


Eligibility

Min Age: 18 YearsMax Age: 100 Years

Plain Language Summary

Simplified for easier understanding

This study evaluates the impact of a medication therapy management (MTM) model — a structured program where pharmacists closely review and optimize a patient's medication regimen — on the safety and effectiveness of anticoagulant (blood-clot preventing) treatment in patients with colorectal cancer who have also developed a blood clot in their veins (venous thromboembolism, or VTE). Cancer patients on blood thinners are at heightened risk of both clotting and bleeding, and pharmacist-led management may help improve outcomes. **You may be eligible if...** - You have histologically confirmed colorectal cancer - You have been diagnosed with a VTE (blood clot) and have been treated with an anticoagulant for at least 3 months - You are currently receiving active anticoagulant treatment **You may NOT be eligible if...** - You are not on active anticoagulant therapy at the time of the study Talk to your doctor to see if this trial is right for you.

This summary was AI-generated to explain the trial in plain language. It is not medical advice. Always discuss eligibility with your doctor before enrolling in a clinical trial.

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Interventions

BEHAVIORALMedication Therapy Management (MTM) model

MTM model comprising five core elements: Medication Therapy Review (MTR), Personal Medication Record (PMR), Medication-Related Action Plan (MAP), interventions \& referrals, and documentation \& follow-up


Locations(1)

Sixth Affiliated Hospital, Sun Yat-sen University

Guangzhou, Guangdong, China

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NCT06998745


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