RecruitingNot ApplicableNCT07000994
Dobutamine During Major Abdominal Surgery
Dobutamine During Major Abdominal Surgery: A Randomized Pilot Trial (PUSH-1)
Sponsor
University of Hamburg-Eppendorf
Enrollment
100 participants
Start Date
Jun 16, 2025
Study Type
INTERVENTIONAL
Conditions
Summary
The PUSH-1 trial is a randomized, single-center pilot trial investigating whether dobutamine administration is feasible in patients having major abdominal surgery.
Eligibility
Min Age: 18 Years
Inclusion Criteria2
- Consenting patients ≥18 years scheduled for elective major abdominal surgery under general anesthesia (expected surgery duration ≥ 120 minutes)
- Planned continuous intraarterial blood pressure monitoring using an arterial catheter for clinical indications not related to the trial
Exclusion Criteria5
- Emergency surgery
- Liver or kidney transplantation surgery
- Status of post transplantation of kidney, liver, heart, or lung
- Pregnancy
- Heart rhythms other than sinus rhythm
Interventions
DRUGDobutamine
In patient assigned to dobutamine administration, dobutamine (concentration: 5 mg mL-1) will be administered with an infusion rate of 3 µg kg-1 min-1 (ideal body weight).
OTHERRoutine care
In patients assigned to routine care, intraoperative hemodynamic management will be in accordance with routine care.
Locations(1)
View Full Details on ClinicalTrials.gov
For the most up-to-date information, visit the official listing.
NCT07000994