RecruitingPhase 4NCT07054775
Comparison of Pruritus Incidence After Intrathecal Morphine 0.1 vs 0.2 mg in Cesarean Section
Comparison of Pruritus Incidence After Intrathecal Morphine 0.1 and 0.2 Milligrams in Cesarean Section: A Randomized Clinical Trial
Sponsor
Khon Kaen University
Enrollment
69 participants
Start Date
Jun 1, 2025
Study Type
INTERVENTIONAL
Conditions
Summary
This study compares the incidence of pruritus (itching) requiring treatment between two doses of intrathecal morphine (0.1 mg vs 0.2 mg) when used for spinal anesthesia during cesarean section. The study aims to determine if the lower dose (0.1 mg) can reduce pruritus incidence while maintaining adequate pain relief.
Eligibility
Sex: FEMALEMin Age: 18 YearsMax Age: 45 Years
Inclusion Criteria4
- Full-term pregnancy
- Scheduled for non-emergency cesarean section
- ASA physical status I-III
- Non-complicated pregnancy
Exclusion Criteria5
- Contraindication to spinal anesthesia or study drugs
- Refusal to participate in the study
- BMI ≥ 40 kg/m²
- History of systemic skin disease or current itchy skin condition
- Use of antihistamines or anti-pruritic medications within 3 days prior to surgery
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Interventions
DRUGMorphine Sulfate
intrathecal administered morphine
Locations(2)
View Full Details on ClinicalTrials.gov
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NCT07054775