RecruitingNot ApplicableNCT07070583

Impact of Aorto-Iliac Occlusive Disease Treatment on Blood Pressure

Impact of Endovascular Treatment of Aorto-iliac Disease on Systemic Hypertension A Pilot Study Impact of Aorto-Iliac Occlusive Disease Treatment on Blood Pressure


Sponsor

Rijnstate Hospital

Enrollment

20 participants

Start Date

Mar 30, 2026

Study Type

INTERVENTIONAL

Conditions

Summary

Hypertension is a major risk factor for a variety of cardiovascular diseases. When hypertension results from increased vascular resistance due to a narrowing of the descending aorta, it can be effectively treated with stenting. More recently, evidence suggest that stenting in more distal parts of the arterial vascular bed is also associated with a reduction in blood pressure. The investigators hypothesize that stenting of occlusions more distal of the descending aorta decreases the central blood pressure and afterload as reflected by NT-proBNP (N-terminal pro-Brain Natriuretic Peptide), a biomarker of intracardiac pressures and predictor of heart failure events. The goal of this pilot study is to prospectively investigate changes in blood pressure after stent placement in the aorto-iliac region.


Eligibility

Min Age: 18 Years

Plain Language Summary

Simplified for easier understanding

This clinical trial is studying a procedure called Stent placement for people with aorto iliac occlusive disease and blood pressure. The study is currently recruiting participants at 1 location. People eligible for this study include aged 18 Years and older.

This summary was AI-generated to explain the trial in plain language. It is not medical advice. Always discuss eligibility with your doctor before enrolling in a clinical trial.

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Interventions

PROCEDUREStent placement

Patients with an aorto-iliac occlusion will receive a stent, according to standard care


Locations(1)

Rijnstate

Arnhem, Netherlands

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NCT07070583


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