RecruitingPhase 2NCT07163819

Effect of Probiotic Intervention on Travel-Related Health Conditions During Short-Term Overseas Travel


Sponsor

Universiti Sains Malaysia

Enrollment

46 participants

Start Date

Jul 31, 2025

Study Type

INTERVENTIONAL

Conditions

Summary

International travel disrupts gut health through dietary changes, microbial exposure, and stress, often causing gastrointestinal symptoms like traveler's diarrhea and sleep disturbances. These shifts may increase antibiotic resistance risks. Probiotics may help stabilize gut microbiota and improve well-being during travel. This randomized, double-blind, placebo-controlled trial investigated whether probiotic supplementation mitigates gut microbiota perturbations, gastrointestinal symptoms, and sleep issues in adults traveling abroad. The investigators also assessed changes in anxiety, well-being, gut immunity, microbial function, and antibiotic resistance genes.


Eligibility

Min Age: 18 YearsMax Age: 65 Years

Plain Language Summary

Simplified for easier understanding

This clinical trial is studying Placebo and Probiotic for people with healthy adults. The study is currently recruiting participants at 2 locations. People eligible for this study include aged 18 Years to 65 Years.

This summary was AI-generated to explain the trial in plain language. It is not medical advice. Always discuss eligibility with your doctor before enrolling in a clinical trial.

Interested in this trial?

Get notified about updates and connect with the research team.

Interventions

OTHERProbiotic

Daily 6-drops of Bifidobacterium longum subsp. infantis M-63, B. breve M-16V, and B. longum BB536 in non-GMO corn starch as excipient, in medium-chain triglyceride oil (1.5 × 109 CFU/day)

OTHERPlacebo

Daily 6-drops of non-GMO corn starch in medium-chain triglyceride oil


Locations(2)

Tsinghua University Science and Technology

Haidian, Beijing Municipality, China

Universiti Sains Malaysia

George Town, Pulau Pinang, Malaysia

View Full Details on ClinicalTrials.gov

For the most up-to-date information, visit the official listing.

Visit

NCT07163819


Related Trials