Feasibility Trial of Combination of Obstetrical Carrier Screening and Hereditary Cancer Screening
Columbia University
1,000 participants
Feb 12, 2026
INTERVENTIONAL
Conditions
Summary
The investigators hypothesize that preconception and pregnancy may be a feasible and effective time to offer inherited cancer risk screening. This study will assess interest in cancer genetic testing among patients receiving routine prenatal care or preconception care. The goal is to evaluate the acceptability of hereditary cancer testing when offered alongside standard prenatal genetic screening. The study will also explore whether universal screening in this population could support early cancer prevention
Eligibility
Inclusion Criteria5
- Age: 18 years - 55 years
- Patients receiving obstetrical-related care at a CUMC-affiliated enrollment site
- Patients who have elected to undergo OCS with the CUMC-affiliated obstetrics provider
- Patients with prior OCS but planned to repeat OCS are eligible
- Patients can speak and read in English or Spanish
Exclusion Criteria3
- Patients who have previously completed a multigene hereditary cancer syndrome panel
- Patients that have a hematologic cancer or hematologic pre-cancer
- Patients who have a history of an autologous bone marrow transplant
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Interventions
Natera Empower Comprehensive Hereditary Cancer Panel to screen for hereditary cancers
Obstetrical carrier screening for genetic conditions
Locations(1)
View Full Details on ClinicalTrials.gov
For the most up-to-date information, visit the official listing.
NCT07195071