RecruitingNot ApplicableNCT07234994

Comparison of the Effect of Ozonized Gel to That of Photobiomodulation Therapy on Wound Healing Following Surgical Gingivectomy

Effect of Ozonized Gel Compared to Photobiomodulation Therapy on Wound Healing Following Surgical Gingivectomy : A Randomized Controlled Clinical Trial


Sponsor

Mennatullah osama ahmed zaki wahba

Enrollment

48 participants

Start Date

Nov 16, 2025

Study Type

INTERVENTIONAL

Conditions

Summary

The goal of this clinical trial is to compare the effect of photobiomodulation to ozonized gel on wound healing following gingivectomy procedure on adults. The main questions it aims to answer are: Which treatment modality provides less painful and more efficient wound healing ? What are the patient's feedback on different treatment modalities ? Researchers will compare ozonized gel to photobiomodulation to normal gingivectomy procedure with no interference. Participants will: Receive either ozonized gel or photobiomodualtion treatment following surgical gingivectomy Visit the clinic every 3,7,14 and 28 days for checkups and investigations


Eligibility

Min Age: 18 YearsMax Age: 40 Years

Inclusion Criteria5

  • Patients indicated for surgical gingivectomy.
  • Adequate amount of keratinized tissue.
  • Average age between 18-40 years.
  • Well-educated patients as post-operative instructions need to be followed precisely.
  • Good oral hygiene with a full mouth O'Leary plaque index of less than or equal to 10% and a full mouth Gingival Index of zero

Exclusion Criteria4

  • History of smoking.
  • Patients who have any known systemic disease that interfere with performance of surgical gingivectomy or periodontal wound healing.
  • Patients who have any previous adverse reactions to the products (or similar products) used in this study.
  • Pregnant women.

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Interventions

DRUGozonized gel application

Application of ozonized gel to raw wound area following surgical gingivectomy.

DEVICEphotobiomodulation therapy using diode laser

Application of diode laser 635nm to wound area following surgical gingivectomy


Locations(1)

Faculty of Dentistry, Alexandria University

Alexandria, Egypt

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NCT07234994


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