RecruitingNot ApplicableNCT07258589

The TASTY-training Study

Taste and Smell Training in Patients With Cancer Who Are Treated With Tyrosine Kinase Inhibitors: a Multicentre Randomized Intervention Trial


Sponsor

University Medical Center Groningen

Enrollment

90 participants

Start Date

Nov 10, 2025

Study Type

INTERVENTIONAL

Conditions

Summary

A multicentre non-blinded randomised intervention trial with a parallel cluster design. The multicentre study will be performed at 12 hospitals in the Netherlands. A parallel cluster design per hospital was selected to prevent contact between participants in the same hospital who are randomised into different study arms. Such contact may result in bias as it may allow for patients in the control arm to be informed about elements of taste and smell training. To examine the effect of at-home taste and smell training versus standard care on taste function and other outcome parameters, measurements will take place at baseline (before the training starts), and after 12 weeks. The intervention will take place at home. The control group will receive usual care. Questionnaires will be filled in online at home, while taste and smell tests and saliva collection will be conducted either at home or in the hospital during regular visits. Patients in both study arms are contacted by their dietitian every 3 weeks.


Eligibility

Min Age: 18 YearsMax Age: 70 Years

Plain Language Summary

Simplified for easier understanding

This clinical trial is studying a behavioral approach called Taste and smell training for people with patients who are treated with tyrosine kinase inhibitors. The study is currently recruiting participants at 11 locations.

This summary was AI-generated to explain the trial in plain language. It is not medical advice. Always discuss eligibility with your doctor before enrolling in a clinical trial.

Interested in this trial?

Get notified about updates and connect with the research team.

Interventions

BEHAVIORALTaste and smell training

To examine the effect of at-home taste and smell training versus standard care on taste function and other outcome parameters, measurements will take place at baseline (before the training starts), and after 12 weeks. The intervention will take place at home. The control group will receive usual care. Questionnaires will be filled in online at home, while taste and smell tests and saliva collection will be conducted either at home or in the hospital during regular visits. Patients in both study arms are contacted by their dietitian every 3 weeks.


Locations(11)

Amsterdam UMC

Amsterdam, Netherlands

Rijnstate Ziekenhuis

Arnhem, Netherlands

Van Weel-Bethesda Ziekenhuis

Dirksland, Netherlands

Ziekenhuisvoorzieningen Gelderse Vallei

Ede, Netherlands

University Medical Center Groningen

Groningen, Netherlands

Martini Ziekenhuis

Groningen, Netherlands

Radboud University medical Center

Nijmegen, Netherlands

Ikazia Ziekenhuis

Rotterdam, Netherlands

Ommelander Ziekenhuis Groningen

Scheemda, Netherlands

Maxima Medisch Centrum

Veldhoven, Netherlands

Isala Klinieken

Zwolle, Netherlands

View Full Details on ClinicalTrials.gov

For the most up-to-date information, visit the official listing.

Visit

NCT07258589


Related Trials