RecruitingPhase 2NCT07260669

A Phase 2 Trial to Investigate Efficacy and Safety of Vipoglanstat in Women With Endometriosis

A Phase 2, Randomized, Double-blind, Placebo-controlled Trial to Investigate the Efficacy and Safety of 2 Doses of Vipoglanstat in Patients With Moderate to Severe Endometriosis-related Pain - the NOVA Trial

Sponsor

Gesynta Pharma AB

Enrollment

190 participants

Start Date

Oct 15, 2025

Study Type

INTERVENTIONAL

Conditions

Endometriosis

Summary

The main objective of the trial is to evaluate the efficacy of vipoglanstat on endometriosis-related non-menstrual pelvic pain (NMPP).

Eligibility

Sex: FEMALEMin Age: 18 YearsMax Age: 44 Years

Plain Language Summary

Simplified for easier understanding

This clinical trial is studying a drug called Placebo and a drug called Vipoglanstat for people with endometriosis. The study is currently recruiting participants at 41 locations. People eligible for this study include women aged 18 Years to 44 Years.

This summary was AI-generated to explain the trial in plain language. It is not medical advice. Always discuss eligibility with your doctor before enrolling in a clinical trial.

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Interventions

DRUGVipoglanstat

Participants will receive vipoglanstat capsules orally for approximately 4 menstrual cycles during the treatment period.

DRUGPlacebo

Participants will receive matching placebo capsules orally for approximately 4 menstrual cycles during the treatment period.

Locations(41)

MHAT Puls AD

Blagoevgrad, Bulgaria

Lyulin Hospital

Sofia, Bulgaria

FemiClinic

Sofia, Bulgaria

Gynekologie MEDA s.r.o

Brno, Czechia

Fakultni nemocnice Brno

Brno, Czechia

NEUMED Gynekologicka Ambulance s.r.o.

Olomouc, Czechia

Gyncare MUDr. Michael Svec s.r.o.

Pilsen, Czechia

STELLA-GYN, s.r.o.

Vodňany, Czechia

MedEnd

Budapest, Hungary

Semmelweis Egyetem II. Sz. Szuleszeti es Nogyogyaszati Klinika

Budapest, Hungary

Robert Karoly Private Hospital Tritonlife Medical Center

Budapest, Hungary

Debreceni Egyetem Klinikai Kozpont

Debrecen, Hungary

Somogy Varmegyei Kaposi Mor Oktato Korhaz (Kaposi Mor County Hospital)

Kaposvár, Hungary

A.O. San Martino Genova Universita di Genova

Genova, Italy

Prywatna Klinika Polozniczo - Ginekologiczna Sp. Z O.O.

Bialystok, Poland

Centrum Ginekologii Artemida

Bialystok, Poland

In- Vivo Sp. z o. o.

Bydgoszcz, Poland

NZOZ Medem

Katowice, Poland

Centrum Medyczne Angelius Provita

Katowice, Poland

NZOZ Vita Longa Sp. z o.o.

Katowice, Poland

Medico Praktyka Lekarska

Krakow, Poland

Centrum Medyczne Chodzki

Lublin, Poland

ETG Siedlce

Siedlce, Poland

Aidport sp. Z o.o.

Skorzewo, Poland

Twoja Przychodnia SCM

Szczecin, Poland

Specjalistyczna Praktyka Lekarska Krzysztof Dynowski

Warsaw, Poland

ETG JustMed

Warsaw, Poland

Genesys Fertility Center

Bucharest, Romania

Delta Health Care

Bucharest, Romania

SC Centrul Medical Unirea SRL - Regina Maria

Iași, Romania

SC Centrul Medical Unirea SRL

Târgu Mureş, Romania

Accellacare Yorkshire

Bradford, United Kingdom

Southmead Hospital - North Bristol NHS Trust

Bristol, United Kingdom

Accellacare Northamptonshire

Corby, United Kingdom

Accellacare Warwickshire

Coventry, United Kingdom

Guy's and St Thomas' NHS Foundation Trust

London, United Kingdom

Accellacare North London

Northwood, United Kingdom

Norfolk and Norwich University Hospital - Norfolk and Norwich University Hospitals NHS Foundation Trust

Norwich, United Kingdom

Accellacare South London

Orpington, United Kingdom

University of Oxford

Oxford, United Kingdom

Southampton General Hospital - University Hospital Southampton NHS Foundation Trust

Southampton, United Kingdom

View Full Details on ClinicalTrials.gov

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NCT07260669

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