RecruitingNCT07322315

Diagnostic Value of Transcranial Doppler Ultrasound for Evaluating Neonatal Craniocerebral Injuries


Sponsor

Kafrelsheikh University

Enrollment

60 participants

Start Date

Jan 6, 2026

Study Type

OBSERVATIONAL

Conditions

Summary

This study aims to evaluate the diagnostic value of transcranial Doppler ultrasonography (TCD) for evaluating neonatal craniocerebral injuries.


Eligibility

Max Age: 37 Weeks

Inclusion Criteria13

  • Both sexes.
  • High-risk neonates with any of the following:
  • Critically ill neonates.
  • Neonatal sepsis.
  • Neonatal encephalopathy includes hypoxic-ischemic encephalopathy.
  • Respiratory distress.
  • Neonatal seizures.
  • Birth asphyxia.
  • Signs and or symptoms of central nervous system disorders like microcephaly, macrocephaly, hypotonia, unexplained poor feeding,
  • Neonates born out of traumatic/instrumental labor.
  • Suspected metabolic disturbances.
  • Neonates with low APGAR score (\<7).
  • Neonates with low birth weight (\<2.5 kg).

Exclusion Criteria3

  • Congenital malformations.
  • Genetic metabolic diseases or other severe complications.
  • Severe intrauterine infection.

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Interventions

DEVICETranscranial Doppler ultrasound

Trans-cranial ultrasound will be carried out for assessment of blood flow velocity in the anterior \[ACA\] and middle cerebral arteries \[MCA\] using duplex pulsed Doppler ultrasound.


Locations(1)

Kafrelsheikh University

Kafr ash Shaykh, Kafrelsheikh, Egypt

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NCT07322315


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