RecruitingNCT07322978

Incidence of Splanchnic Venous Thrombosis in Acute Pancreatitis and it's Correlation With Severity of Pancreatitis

Incidence of Splanchnic Venous Thrombosis in Acute Pancreatitis and it's Correlation With Severity of Pancreatitis - a Prospective Observational Study


Sponsor

Asian Institute of Gastroenterology, India

Enrollment

500 participants

Start Date

Feb 27, 2025

Study Type

OBSERVATIONAL

Conditions

Summary

Acute pancreatitis (AP) is a common medical condition characterized by inflammation of the pancreas, affecting a significant portion of the population. With approximately one-third of patients experiencing notable morbidity due to local or systemic complications, the severity of the disease is underscored by the presence of acute peripancreatic fluid collections, acute necrotic collections, pseudocysts, and walled-off necrosis1. Notably, vascular complications, such as splanchnic vein thrombosis, further contribute to the increased morbidity and mortality associated with acute pancreatitis2. Splanchnic vein thrombosis encompasses thromboses in the splenic (SpVT), portal (PVT), and superior mesenteric veins (SMVT), either individually or in combination3. These complications are often incidentally discovered during imaging procedures conducted to assess potential complications4. Despite most cases being asymptomatic, fatal complications, including bowel ischemia, liver failure, portal hypertension, and life-threatening bleeding, have been documented, with the risk of splanchnic vein thrombosis escalating with the severity of pancreatitis


Eligibility

Min Age: 18 YearsMax Age: 85 Years

Inclusion Criteria2

  • Patients aged between 18-85 years of age.
  • Diagnosis of AP as per international consensus criteria.

Exclusion Criteria4

  • Chronic pancreatitis.
  • Established malignancy.
  • Cirrhosis of liver or established portal hypertension.
  • Pregnancy.

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Locations(1)

AIG Hospital

Hyderabad, Telangana, India

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NCT07322978


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