RecruitingNCT07347925

Effect of Pre-Hospital ARNI Therapy on Short-Term Outcomes in HFrEF

Evaluating the Impact of Pre-Hospital Angiotensin Receptor-Neprilysin Inhibitor (ARNI) Therapy on Short-Term Clinical Outcomes in Heart Failure Patients With Reduced Ejection Fraction: A Comparative Study


Sponsor

Future University in Egypt

Enrollment

140 participants

Start Date

Jan 10, 2026

Study Type

OBSERVATIONAL

Conditions

Summary

This study looks at people with heart failure who are admitted to the hospital. The goal of the study is to understand whether taking a heart failure medicine called angiotensin receptor-neprilysin inhibitor (ARNI) before hospital admission affects short-term health outcomes. The study will compare two groups of participants: those who were already taking ARNI before coming to the hospital and those who were not. Information will be collected from medical records during the hospital stay, including heart-related events, kidney-related events, and how long participants stay in the hospital. Some participants will also be followed for a short period after discharge. This study may help improve understanding of outcomes associated with ARNI use in people with heart failure in routine clinical care.


Eligibility

Min Age: 18 Years

Inclusion Criteria1

  • \>= 18 years, male or female EF \<40%

Exclusion Criteria1

  • EF\>40% Pregnancy or breastfeeding

Interventions

OTHERPrehospital ARNI use

Participants who were using ARNI therapy before hospital admission

OTHERNo prehospital ARNI use

Participants who were not using ARNI therapy before hospital admission


Locations(1)

Mansoura university Hospital

Al Mansurah, Egypt

View Full Details on ClinicalTrials.gov

For the most up-to-date information, visit the official listing.

Visit

NCT07347925


Related Trials