Effect of Pre-Hospital ARNI Therapy on Short-Term Outcomes in HFrEF
Evaluating the Impact of Pre-Hospital Angiotensin Receptor-Neprilysin Inhibitor (ARNI) Therapy on Short-Term Clinical Outcomes in Heart Failure Patients With Reduced Ejection Fraction: A Comparative Study
Future University in Egypt
140 participants
Jan 10, 2026
OBSERVATIONAL
Conditions
Summary
This study looks at people with heart failure who are admitted to the hospital. The goal of the study is to understand whether taking a heart failure medicine called angiotensin receptor-neprilysin inhibitor (ARNI) before hospital admission affects short-term health outcomes. The study will compare two groups of participants: those who were already taking ARNI before coming to the hospital and those who were not. Information will be collected from medical records during the hospital stay, including heart-related events, kidney-related events, and how long participants stay in the hospital. Some participants will also be followed for a short period after discharge. This study may help improve understanding of outcomes associated with ARNI use in people with heart failure in routine clinical care.
Eligibility
Inclusion Criteria1
- \>= 18 years, male or female EF \<40%
Exclusion Criteria1
- EF\>40% Pregnancy or breastfeeding
Interventions
Participants who were using ARNI therapy before hospital admission
Participants who were not using ARNI therapy before hospital admission
Locations(1)
View Full Details on ClinicalTrials.gov
For the most up-to-date information, visit the official listing.
NCT07347925