Peripheral Autonomic Block (BAP) Plus Transversus Abdominis Plane Block (TAP) for Postoperative Analgesia After Minimally Invasive Left-Sided Colorectal Resection (BAPTAP)
Peripheral Autonomic Block (BAP) Plus Transversus Abdominis Plane Block (TAP) for Postoperative Analgesia After Minimally Invasive Left-Sided Colorectal Resection (BAPTAP): A Randomized, Controlled, Double-Blind Trial
Faculdade de Ciências Médicas de Minas Gerais
140 participants
Feb 12, 2026
INTERVENTIONAL
Conditions
Summary
Effective postoperative pain management is essential for enhanced recovery after laparoscopic colorectal surgery. This randomized, controlled, double-blind trial will compare conventional postoperative analgesia (intravenous medications plus surgical wound infiltration) with a locoregional strategy combining a peripheral autonomic block (inferior mesenteric and superior hypogastric plexuses) and a transversus abdominis plane (TAP) block. We hypothesize that the combined strategy (BAPTAP) reduces pain intensity and opioid consumption in the first 48 hours after Left-Sided Colorectal Resection.
Eligibility
Inclusion Criteria3
- Elective laparoscopic left-sided colorectal resection
- ASA physical status I-II
- Ability to understand the study and sign informed consent
Exclusion Criteria6
- Known allergy to study medications (e.g., local anesthetics)
- Coagulation disorders
- Pregnancy
- Inability to understand or provide consent
- Chronic pain on opioid therapy
- BMI \> 35 kg/m²
Interventions
Elective laparoscopic anterior/rectosigmoid resection or sigmoid colectomy per institutional standards; not randomized.
General anesthesia combined with peripheral autonomic plexus blockade (superior hypogastric and inferior mesenteric plexuses) using 0.2% ropivacaine, 8 mL per site; performed laparoscopically prior to dissection, in association with bilateral ultrasound-guided TAP block with 0.33% ropivacaine, 30 mL per side.
General anesthesia with trocar/incision infiltration using 0.33% ropivacaine, up to a total volume of 60 mL.
Locations(1)
View Full Details on ClinicalTrials.gov
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NCT07388953