RecruitingPhase 2NCT07402551

Phase II Study of RC1416 Injection in COPD

A Multicenter, Randomized, Double-Blind, Placebo-Controlled Phase II Clinical Study to Evaluate the Efficacy and Safety of RC1416 Injection in Patients With Moderate to Severe Chronic Obstructive Pulmonary Disease (COPD)

Sponsor

Nanjing RegeneCore Biotech Co., Ltd.

Enrollment

180 participants

Start Date

Mar 6, 2026

Study Type

INTERVENTIONAL

Conditions

Moderate to Severe Chronic Obstructive Pulmonary Disease (COPD)

Summary

This is a multicenter, randomized, double-blind, placebo-controlled phase II clinical study to evaluate the efficacy and safety of RC1416 injection in patients with moderate to severe chronic obstructive pulmonary disease (COPD).

Eligibility

Min Age: 40 YearsMax Age: 85 Years

Plain Language Summary

Simplified for easier understanding

This clinical trial is studying a drug called RC1416 and a drug called RC1416 Placebo for people with moderate to severe chronic obstructive pulmonary disease (copd). The study is currently recruiting participants at 41 locations. People eligible for this study include aged 40 Years to 85 Years.

This summary was AI-generated to explain the trial in plain language. It is not medical advice. Always discuss eligibility with your doctor before enrolling in a clinical trial.

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Interventions

DRUGRC1416

There are two doses in this part. Each subjects will receive the drug by subcutaneous injection.

DRUGRC1416 Placebo

Each subjects will receive the placebo by subcutaneous injection.

Locations(41)

Anhui Provincial Chest Hospital

Hefei, Anhui, China

Wan Bei General Hospital of Wanbei Coal power Group

Suzhou, Anhui, China

The Affiliated Bishan Hospital of Chongqing Medical University

Chongqing, Chongqing Municipality, China

Zhongshan Hospital Xiamen University

Xiamen, Fujian, China

The first affiliated hospital of guangzhou medical university

Guangzhou, Guangdong, China

The First Affiliated Hospital of Jinan University

Guangzhou, Guangdong, China

The first affiliated hospital of guangzhou medical university

Guangzhou, Guangdong, China

Huizhou Third People's Hospital

Huizhou, Guangdong, China

Jiangmen Central Hospital

Jiangmen, Guangdong, China

Guangzhou Medical University Affiliated Qingyuan Hospital (Qingyuan People's Hospital)

Qingyuan, Guangdong, China

The First Affiliated Hospital of guangxi Medical University

Nanning, Guangxi, China

The First People's Hospital of Yulin

Yulin, Guangxi, China

Affiliated Hospital of Zunyi Medical University

Zunyi, Guizhou, China

Anyang People's Hospital

Anyang, Henan, China

Jiaozuo Second People's Hospital

Jiaozuo, Henan, China

Nanyang First People's Hospital

Nanyang, Henan, China

Nanyang Second People's Hospital

Nanyang, Henan, China

Sanmenxia Central Hospital

Sanmenxia, Henan, China

Xinxiang First People's Hospital

Xinxiang, Henan, China

Yichang Central People's Hospital

Yichang, Hubei, China

Loudi Central Hospital

Loudi, Hunan, China

The Affiliated Hospital of Inner Mongolia Medical University

Hohhot, Inner Mongolia, China

The First People's Hospital of Lianyungang City

Lianyungang, Jiangsu, China

Nanjing First Hospital

Nanjing, Jiangsu, China

Xuzhou Central Hospital

Xuzhou, Jiangsu, China

Yangzhou University Affiliated Hospital

Yangzhou, Jiangsu, China

Jiu Jiang NO.1 People's Hospital

Jiujiang, Jiangxi, China

People's Hospital of Pingxiang City

Pingxiang, Jiangxi, China

The Second Hospital of Jilin University

Changchun, Jilin, China

Shengjing Hospital of China Medical University

Shenyang, Liaoning, China

LiaoCheng People's Hospital

Liaocheng, Shandong, China

Qingdao Municipal Hospital

Qingdao, Shandong, China

The Second People's Hospital of Weifang

Weifang, Shandong, China

Zibo Municipal Hospital

Zibo, Shandong, China

Shanghai Pulmonary Hospital

Shanghai, Shanghai Municipality, China

The Third People's Hospital of Chengdu City

Chengdu, Sichuan, China

Chengdu Fifth People's Hospital

Chengdu, Sichuan, China

Mianyang central hospital

Mianyang, Sichuan, China

Suining Central Hospital

Suining, Sichuan, China

Zigong First People's Hospital Zigong Academy of Medicalsciences

Zigong, Sichuan, China

The 2nd Affiliated Hospital and Yuying Children's Hospital of WMU

Wenzhou, Zhejiang, China

View Full Details on ClinicalTrials.gov

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NCT07402551