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RecruitingPhase 1NCT07437105

Dose Escalation Study Evaluating the Safety and Pharmacokinetics of VX-272 in Healthy Participants

A Phase 1, Randomized, Double-blind, Placebo-controlled, Dose Escalation Study Evaluating Safety and Pharmacokinetics of VX-272 in Healthy Subjects

Sponsor

Vertex Pharmaceuticals Incorporated

Enrollment

128 participants

Start Date

Feb 25, 2026

Study Type

INTERVENTIONAL

Conditions

Cystic Fibrosis

Summary

The purpose of this study is to evaluate the safety, tolerability and pharmacokinetics of single and multiple ascending doses of VX-272.

Eligibility

Min Age: 18 YearsMax Age: 55 Years

Plain Language Summary

Simplified for easier understanding

This clinical trial is studying a drug called Placebo and a drug called VX-272 for people with cystic fibrosis. The study is currently recruiting participants at 1 location. People eligible for this study include aged 18 Years to 55 Years.

This summary was AI-generated to explain the trial in plain language. It is not medical advice. Always discuss eligibility with your doctor before enrolling in a clinical trial.

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Interventions

DRUGVX-272

Suspension for Oral Administration.

DRUGPlacebo

Suspension for Oral Administration.

Locations(1)

Celerion - Tempe

Tempe, Arizona, United States

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NCT07437105

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