RecruitingNCT07482228

Long-term Clinical Outcomes After Retinal Artery Occlusion

Long-Term Cardiovascular and Cerebrovascular Outcomes After Retinal Artery Occlusion: A Nationwide Study


Sponsor

Chonnam National University Hospital

Enrollment

15,000 participants

Start Date

Mar 1, 2026

Study Type

OBSERVATIONAL

Conditions

Summary

Retinal artery occlusion (RAO) is a rare but vision-threatening vascular disorder that is commonly caused by embolic events originating from the heart or carotid arteries. Patients with RAO are known to have an increased risk of subsequent cardiovascular and cerebrovascular events, including ischemic stroke and myocardial infarction. However, long-term outcomes and optimal medical treatment strategies for these patients remain insufficiently characterized. The purpose of this nationwide population-based study is to investigate the incidence of long-term cardiovascular and cerebrovascular outcomes in patients diagnosed with retinal artery occlusion using the Korean National Health Insurance Service (NHIS) database. In addition, the study aims to evaluate the impact of various medical therapies, including antiplatelet agents, anticoagulants, and statins, on long-term clinical outcomes.


Eligibility

Inclusion Criteria1

  • Patients newly diagnosed with retinal artery occlusion

Exclusion Criteria2

  • Patients with a prior diagnosis of retinal artery occlusion before the study period.
  • Patients diagnosed with giant cell arteritis.

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Interventions

OTHERretinal artery occlusion

treatment for retinal artery occlusion


Locations(1)

Chonnam National University Hospital

Gwangju, Gwangju, South Korea

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NCT07482228