RecruitingNot ApplicableNCT07515612

The Impact of Valerian and Chamomile on Children's Anxiety in the Dental Clinic.

The Effect of Valerian and Chamomile on Pediatric Dental Anxiety: A Randomized Controlled Trial

Sponsor

Damascus University

Enrollment

78 participants

Start Date

Dec 1, 2025

Study Type

INTERVENTIONAL

Conditions

Anxiety, Dental

Summary

This randomized controlled clinical trial aims to evaluate and compare the effectiveness of chamomile extract and valerian extract in reducing dental anxiety in healthy pediatric patients aged 6 to 10 years undergoing tooth extraction. Participants will be randomly assigned to receive one of the herbal interventions or a placebo prior to extraction. Dental anxiety will be assessed using validated anxiety rating scales and physiological parameters. This study seeks to explore a safe, easy to apply, and effective approach to manage child behavior and reduce dental anxiety.

Eligibility

Min Age: 6 YearsMax Age: 10 Years

Inclusion Criteria2

\. Healthy children with no systemic or mental diseases. 2. Children aged 6-10 years. 4. Children with positive behavior according to the Frankl behavior rating scale.
\. Children requiring a simple tooth extraction of upper primary molars under local anesthesia.

Exclusion Criteria4

Children whose parents refused participation in the study.
Children who were unwilling to ingest any of the herbal extracts.
Children with a history of hypersensitivity to chamomile or valerian.
Children who had taken any sedative, anxiolytic or analgesic medications within the last 8 hours prior to treatment.

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Interventions

DIETARY_SUPPLEMENTValerian extract

Participants will receive 1 mL of valerian root liquid extract (Valeriana officinalis L., 1000 mg/mL), diluted in a small amount of apple juice, 30 minutes prior to local anesthesia and tooth extraction.

DIETARY_SUPPLEMENTChamomile extract

Participants will receive 2 ml of German chamomile flower liquid extract (Matricaria recutita, 2400 mg/2 mL), diluted in a small amount of water, 30 minutes prior to local anesthesia and tooth extraction.

OTHERWater (Placebo)

Participants will receive a small amount of water 30 minutes prior to local anesthesia and tooth extraction.

Locations(1)

Department of Pediatric Dentistry, Faculty of Dentistry, Damascus University

Damascus, Syria

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NCT07515612