Phase 4 Action Clinical Trials
53 recruitingPhase 4
What is a Phase 4 trial?
Phase 4 trials, also called post-marketing studies, are conducted after a treatment has been approved and is available to the public. They monitor long-term effectiveness and safety in a broader population.
Showing 1–20 of 53 trials
Recruiting
Phase 4
The Effects of Propranolol and Hydrocortisone on Military-Relevant Performance Outcomes
Acute Stress ReactionFear of Spiders
Walter Reed Army Institute of Research (WRAIR)88 enrolled1 locationNCT06982183
Recruiting
Phase 4
The Effect of Different Types of Mouthwash on Extraction Sockets' Healing
Quality of LifePostoperative ComplicationsExtraction Socket Healing
University of Jordan100 enrolled1 locationNCT06587880
Recruiting
Phase 4
Epicardial Adipose Tissue Composition and Heart Failure With Preserved Ejection Fraction
Heart Failure Preserved Ejection FractionEpicardial Adipose Tissue
University of Virginia192 enrolled1 locationNCT07178145
Recruiting
Phase 4
An Extension Test of Whether to Use Oral Anti-anxiety Drugs (Alprazolam) When Patients Choose Second Eye Cataract Surgery After Unblinding, and Analyze Their Anxiety, Satisfaction and Pain Satisfaction
OphthalmologyCataract Surgery AnesthesiaOral Anxiolytic+1 more
National Taiwan University Hospital250 enrolled1 locationNCT06874452
Recruiting
Phase 4
Study Evaluating the Safety and Efficacy of Neffy or Intramuscular Adrenalin in Patients With Allergic Reactions After Oral Food Challenge or Allergen Immunotherapy
Allergic Reactions
ARS Pharmaceuticals, Inc.600 enrolled6 locationsNCT06834165
Recruiting
Phase 4
Antihistamine for Prevention of HTR After Blood Primed CPB
Blood Transfusion Associated Adverse Reactions
Kasr El Aini Hospital40 enrolled1 locationNCT07536152
Recruiting
Phase 4
Mechanistic Clinical Trial Comparing the Pharmacokinetics/Pharmacodynamics of Metoprolol in Heart Failure With Reduced Ejection Fraction Patients With Low vs. High Polygenic Score
Heart Failure With Reduced Ejection Fraction
University of Michigan100 enrolled1 locationNCT07490067
Recruiting
Phase 4
Evaluating the Safety of Shortened Infusion Times for dIfferent Oncological Immunotherapie
OncologyInfusion Reaction
Isala776 enrolled1 locationNCT06031233
Not Yet Recruiting
Phase 4
Volumetric and histological outcomes of platelet derived growth factor use in alveolar ridge preservation after dental extractions
Healing of dental extraction sockets
The University of Melbourne30 enrolled1 locationACTRN12626000228381
Recruiting
Phase 4
Impact of Intravenous Iron Repletion On Mechanisms of Exercise InTolerance in HFpEF (IRONMET-HFpEF)
Iron-deficiencyHeart Failure With Preserved Ejection Fraction
Massachusetts General Hospital66 enrolled1 locationNCT04945707
Recruiting
Phase 4
Colchicine's Effect on Inflammatory Markers
ColchicinePost-operative Atrial FibrillationInflammation in Cardiac Surgery+2 more
Ayesha Ather24 enrolled1 locationNCT07287345
Recruiting
Phase 4
Vericiguat and Reverse Remodeling Indices in Heart Failure
Heart Failure With Reduced Ejection Fraction (HFrEF)Chronic Heart Failure
University Medical Centre Ljubljana60 enrolled1 locationNCT07405944
Recruiting
Phase 4
Intrathecal Versus Epidural Morphine for Post-Cesarean Analgesia
Patient SatisfactionPost Operative PainAnalgesia+2 more
Hospital Central do Funchal120 enrolled1 locationNCT07386353
Recruiting
Phase 4
Steroid Use in Treatment of Allergic Reactions to Food
AnaphylaxisIgE-mediated food allergyAnaphylactic Reaction+1 more
Johannes Trueck160 enrolled2 locationsNCT07341776
Recruiting
Phase 4
Single and Twice-daily Dosing of Ramipril on Renal Function in Chronic Kidney Disease Patients With Reduced Ejection Fraction Heart Failure
Chronic Kidney DiseaseHeart Failure With Reduced Ejection Fraction (HFrEF)
Evi Liliek Wulandari80 enrolled1 locationNCT07259512
Recruiting
Phase 4
Cognitive Outcomes After Dexmedetomidine Sedation in Cardiac Surgery Patients
ConfusionCognitive DysfunctionMolecular Mechanisms of Pharmacological Action+14 more
Sunnybrook Health Sciences Centre2,400 enrolled8 locationsNCT04289142
Recruiting
Phase 4
Comparative Effectiveness of Carvedilol Versus Metoprolol Succinate in Heart Failure Patients With an Implantable Cardioverter Defibrillator
CardiomyopathySudden Cardiac DeathHeart Failure With Reduced Ejection Fraction (HFrEF)+3 more
University of Rochester2,000 enrolled13 locationsNCT06964464
Recruiting
Phase 4
Pioglitazone on Heart Failure in Type-2 Diabetes Mellitus Participants
Type 2 Diabetes Mellitus in ObeseHeart Failure With Preserved Ejection Fraction
The University of Texas Health Science Center at San Antonio78 enrolled1 locationNCT05838287
Recruiting
Phase 4
Effect of Mannitol on Propofol Level
Mannitol Adverse Reaction
Cukurova University40 enrolled1 locationNCT06884657
Recruiting
Phase 4
Oral Contraceptive Pill (OCP) Pharmacogenomics
ContraceptionPharmacogenomic Drug Interaction
Yale University700 enrolled2 locationsNCT06334315