Early Phase 1 AD Clinical Trials
133 recruitingEarly Phase 1
What is a Early Phase 1 trial?
Early Phase 1 trials are the earliest stage of testing in humans. These small studies focus on how a drug is processed in the body and how it affects the body, often enrolling just a handful of participants to establish initial safety data.
Showing 1–20 of 133 trials
Recruiting
Early Phase 1
NK521 in the Treatment of Malignant Ascites Associated With Advanced Solid Tumors
Advanced Solid Tumors
Base Therapeutics (Shanghai) Co., Ltd.18 enrolled1 locationNCT07561437
Recruiting
Early Phase 1
The Dosimetry, Safety and Diagnostic Efficacy of ⁶⁸Ga-FC516 in Healthy Subjects and Patients With Prostate Cancer
Prostate CancerHealthy Adult
FindCure Biosciences (ZhongShan) Co., Ltd.10 enrolled1 locationNCT07468708
Recruiting
Early Phase 1
Evaluation of 18F-Fluciclovine Positron Emission Tomography - Magnetic Resonance Imaging (PET-MRI) in LGG
GliomaGlioma, MalignantLow-grade Glioma+2 more
Children's Hospital of Philadelphia30 enrolled1 locationNCT05555550
Recruiting
Early Phase 1
Window Trial of Fluorescently Labeled Nivolumab-IRDye800 (Nivo800) in High Grade Glioma (HGG)
Brain CancerGliomaHigh Grade Glioma+1 more
Eben Rosenthal38 enrolled1 locationNCT07210632
Recruiting
Early Phase 1
First-in-human Study of the Theranostic Pair [68Ga]Ga DOTA-5G and [177Lu]Lu DOTA-ABM-5G in Pancreatic Cancer
Metastatic Pancreatic CancerLocally Advanced Pancreatic Adenocarcinoma
University of California, Davis30 enrolled1 locationNCT04665947
Recruiting
Early Phase 1
Concomitant Renal and Urinary Bladder Allograft Transplantation
Chronic Kidney DiseasesBladder DysfunctionNeurogenic Bladder+6 more
Mayo Clinic30 enrolled2 locationsNCT04626167
Recruiting
Early Phase 1
Safety and Feasibility of HIPEC for High-Risk Gallbladder Adenocarcinoma
Gallbladder Adenocarcinoma
West Virginia University10 enrolled1 locationNCT05430035
Recruiting
Early Phase 1
Donor Virus-Specific CMV or AdV CTL to Treat CMV or AdV Reactivation or Disease After Solid Organ or HCT
Allogeneic Hematopoietic Stem Cell Transplantation RecipientAdenovirusCytomegalovirus+2 more
Sumithira Vasu20 enrolled2 locationsNCT03665675
Recruiting
Early Phase 1
Neurobehavioral Mechanisms Linking Childhood Adversity to Increased Risk for Smoking
Nicotine Dependence, CigarettesAdverse Childhood Experiences
Duke University150 enrolled1 locationNCT05665465
Recruiting
Early Phase 1
Adaptive Therapy of Vismodegib in Advanced Basal Cell Carcinoma
Advanced Basal Cell Carcinoma
H. Lee Moffitt Cancer Center and Research Institute34 enrolled1 locationNCT05651828
Recruiting
Early Phase 1
Clinical Study on the Efficacy and Safety of CAR-DC in the Treatment of Advanced Solid Tumors
Advanced Solid Tumors
Peking University Shenzhen Hospital10 enrolled1 locationNCT07504445
Recruiting
Early Phase 1
OMO-103 for the Treatment of Locally Advanced or Metastatic Pancreatic Ductal Adenocarcinoma
Stage II Pancreatic Cancer AJCC v8Stage III Pancreatic Cancer AJCC v8Stage IV Pancreatic Cancer AJCC v8+2 more
OHSU Knight Cancer Institute12 enrolled1 locationNCT07089940
Recruiting
Early Phase 1
Using a PET Imaging Agent, 18F-Clofarabine (CFA), to Measure Deoxycytidine Kinase Activity in Metastatic Cancer
Metastatic CancerCarcinomaAdenocarcinoma
Roberto Vargas4 enrolled1 locationNCT05065736
Recruiting
Early Phase 1
Fecal Microbial Transplants for the Treatment of Pancreatic Cancer
Pancreatic Ductal Adenocarcinoma
M.D. Anderson Cancer Center10 enrolled1 locationNCT04975217
Recruiting
Early Phase 1
A Pilot Study of Larotrectinib for Newly-Diagnosed High-Grade Glioma With NTRK Fusion
High Grade GliomaDiffuse Intrinsic Pontine Glioma
Nationwide Children's Hospital15 enrolled21 locationsNCT04655404
Recruiting
Early Phase 1
Advancing VR-based Attentional Bias as a Biomarker for Tobacco Use Disorder
Nicotine AddictionCraving
University of California, San Diego200 enrolled1 locationNCT06582888
Recruiting
Early Phase 1
iMagemHTT-009- FIH Evaluation of Novel Mutant Huntingtin PET Radioligand [11C]CHDI-00491009
Huntington DiseasePositron Emission TomographyImaging+5 more
CHDI Foundation, Inc.27 enrolled1 locationNCT06634628
Recruiting
Early Phase 1
Exploratory Clinical Study of Targeted Activated DC and CAR-T Therapy in Advanced Solid Cancers
Advanced Solid Cancers
Hainan Cancer Hospital10 enrolled1 locationNCT07475182
Recruiting
Early Phase 1
Lorlatinib for Newly-Diagnosed High-Grade Glioma With ROS or ALK Fusion
GlioblastomaGlioblastoma MultiformeHigh Grade Glioma+6 more
Nationwide Children's Hospital15 enrolled18 locationsNCT06333899
Recruiting
Early Phase 1
A Phase I Study to Evaluate the Safety, Tolerability, and PK of HLX37 in Advanced/Metastatic Solid Tumors
NSCLCAdvanced/Metastatic Solid Tumors
Shanghai Henlius Biotech254 enrolled2 locationsNCT07274813