Amyloidosis Clinical Trials in Cleveland, Ohio

10 recruitingCleveland, Ohio

Showing 110 of 10 trials

Recruiting
Phase 3

TRITON-CM: A Study to Evaluate Nucresiran in Patients With Transthyretin Amyloidosis With Cardiomyopathy

Transthyretin Amyloidosis With Cardiomyopathy
Alnylam Pharmaceuticals1,250 enrolled207 locationsNCT07052903
Recruiting
Phase 3

Acoramidis Transthyretin Amyloidosis Prevention Trial in the Young (ACT-EARLY) Study in Asymptomatic Carriers of a Pathogenic TTR Variant

CardiomyopathiesAmyloidosisHeart Diseases+3 more
Eidos Therapeutics, a BridgeBio company582 enrolled98 locationsNCT06563895
Recruiting
Phase 1Phase 2

A Phase 1b/2 Study of CAR T Cell Therapy Targeting CD19 and BCMA in Participants With Relapsed or Refractory AL Amyloidosis.

AmyloidosisLight Chain AmyloidosisRelapsed AL Amyloidosis+1 more
Alexion Pharmaceuticals, Inc.91 enrolled18 locationsNCT07081646
Recruiting
Phase 3

MAGNITUDE: A Phase 3 Study of NTLA-2001 in Participants With Transthyretin Amyloidosis With Cardiomyopathy (ATTR-CM)

Transthyretin Amyloidosis (ATTR) With Cardiomyopathy
Intellia Therapeutics1,200 enrolled132 locationsNCT06128629
Recruiting

Analysis of Lumbar Spine Stenosis Specimens for Identification of Transthyretin Cardiac Amyloidosis

Cardiac AmyloidosisCardiomyopathy, HypertrophicLumbar Spinal Stenosis+3 more
Columbia University1,663 enrolled6 locationsNCT06034405
Recruiting
Phase 4

Safety, Efficacy, and Pharmacokinetics of Tafamidis in Patients With Transthyretin-mediated Amyloidosis Post Orthotopic Heart Transplantation

Transthyretin Cardiac Amyloidosis
University of Texas Southwestern Medical Center25 enrolled4 locationsNCT05489523
Recruiting
Phase 2

A Study of AT-02 in Subjects With Systemic Amyloidosis.

Amyloidosis; Systemic
Attralus, Inc.120 enrolled4 locationsNCT05951049
Recruiting
Phase 1Phase 2

Study of NXC-201 CAR-T in Patients With Light Chain (AL) Amyloidosis

Light Chain (AL) Amyloidosis
Nexcella Inc.40 enrolled18 locationsNCT06097832
Recruiting

Subclinical Transthyretin Cardiac Amyloidosis in V122I TTR Carriers

Amyloidosis CardiacAmyloidosis, HereditaryAmyloidosis, Familial+2 more
University of Texas Southwestern Medical Center500 enrolled3 locationsNCT05489549
Recruiting
Phase 1

Study of AT-02 in Healthy Volunteers and Subjects With Systemic Amyloidosis

Amyloidosis; Systemic
Attralus, Inc.100 enrolled11 locationsNCT05521022