Phase 2 Anger Clinical Trials

9 recruitingPhase 2

What is a Phase 2 trial?

Phase 2 trials evaluate whether a treatment works for a specific condition and further assess its safety. These studies typically enroll several hundred participants and provide preliminary data on effectiveness.

Showing 19 of 9 trials

Recruiting
Phase 2

A Study With Tovorafenib (DAY101) as a Treatment Option for Progressive, Relapsed, or Refractory Langerhans Cell Histiocytosis

Recurrent Langerhans Cell HistiocytosisRefractory Langerhans Cell Histiocytosis
National Cancer Institute (NCI)48 enrolled117 locationsNCT05828069
Recruiting
Phase 2

Targeted Approach to Langerhans Cell Histiocytosis (LCH) Using MEK Inhibitor, Trametinib

Langerhans Cell Histiocytosis
Cook Children's Health Care System75 enrolled1 locationNCT06582745
Recruiting
Phase 2

Efficacy and Safety of Low-Dose Cytarabine Combined With Thalidomide in Adult Patients With Untreated LCH

Langerhans Cell Histiocytosis
Cancer Institute and Hospital, Chinese Academy of Medical Sciences50 enrolled1 locationNCT07187193
Recruiting
Phase 2

Cobimetinib in Refractory Langerhans Cell Histiocytosis (LCH), and Other Histiocytic Disorders

Langerhan's Cell HistiocytosisJuvenile XanthogranulomaErdheim-Chester Disease+4 more
Carl Allen90 enrolled12 locationsNCT04079179
Recruiting
Phase 2

Mirdametinib in Histiocytic Disorders

Histiocytic DisordersRosai-Dorfman Disease (RDD)Langerhans Cell Histiocytosis (LCH)+1 more
Children's Hospital Medical Center, Cincinnati40 enrolled1 locationNCT06153173
Recruiting
Phase 2

Real-world Study of Darafenib or Trametinib and Clofarabine for High-risk/Recurrent/Refractory Langerhans Cell Histiocytosis in Children

Langerhans Cell Histiocytosis (LCH)
West China Second University Hospital20 enrolled1 locationNCT07022834
Recruiting
Phase 2Phase 3

LCH-IV, International Collaborative Treatment Protocol for Children and Adolescents With Langerhans Cell Histiocytosis

Langerhans Cell Histiocytosis
North American Consortium for Histiocytosis1,400 enrolled42 locationsNCT02205762
Recruiting
Phase 2

To Evaluate the Efficacy, Safety, and PK Characteristics of FCN-159 in Pediatric Patients With Refractory/Recurrent LCH

Langerhans Cell HistiocytosisLCH
Shanghai Fosun Pharmaceutical Industrial Development Co. Ltd.56 enrolled11 locationsNCT05997602
Recruiting
Phase 2

Oral Prednisone in Treating LCH of Bone in Childhood and Adolescence

Langerhans Cell Histiocytosis of Bone
Shanghai Changzheng Hospital118 enrolled1 locationNCT06078969