Phase 1 Atopic Clinical Trials
40 recruitingPhase 1
What is a Phase 1 trial?
Phase 1 trials test a new treatment in a small group of people for the first time. The primary goal is to evaluate safety, determine a safe dosage range, and identify side effects. These studies typically enroll 20 to 80 participants.
Showing 1–20 of 40 trials
Recruiting
Phase 1
Evaluating the Safety and Tolerability of Baricitinib in Patients With Job Syndrome With Lupus-Like Disease and/or Atopic Dermatitis
Atopic DermatitisLupusHyper IgE Syndrome From STAT3 Mutation+2 more
National Institute of Allergy and Infectious Diseases (NIAID)20 enrolled1 locationNCT07262983
Recruiting
Phase 1
A Study of BBT001 in Healthy Volunteers (HVs) and in Adult Patients With Moderate to Severe Atopic Dermatitis (AD)
Atopic Dermatitis
Bambusa Therapeutics99 enrolled10 locationsNCT07239947
Recruiting
Phase 1
FIH Study to Evaluate the Tolerability of PF-07832837 in Healthy Adults and Patients
Healthy ParticipantsAtopic Dermatitis
Pfizer119 enrolled5 locationsNCT06564389
Recruiting
Phase 1
A First-in-human Study to Investigate Single Doses of DCY636 in Healthy Volunteers and Multiple Doses in Participants With Moderate to Severe Atopic Dermatitis
Dermatitis Atopic
Novartis Pharmaceuticals63 enrolled1 locationNCT07604324
Recruiting
Phase 1
Single Ascending and Multiple Ascending Dose Study of LCA-0061
atopic diseasePeanut Allergies
Lycia Therapeutics, Inc.72 enrolled1 locationNCT07701954
Recruiting
Phase 1
A Study of BBT001 in Healthy Volunteers (HVs) and in Adult Patients With Atopic Dermatitis (AD)
Atopic Dermatitis
Bambusa Therapeutics237 enrolled14 locationsNCT06808477
Recruiting
Phase 1
Targeted Investigation of Microbiome 2 Treat Atopic Dermatitis (TIME-2)
Atopic Dermatitis
National Institute of Allergy and Infectious Diseases (NIAID)86 enrolled8 locationsNCT06504160
Recruiting
Phase 1
First-in-Human Trial to Assess REGN20423 in Healthy Adult Participants and Adult Participants With Atopic Dermatitis
Healthy VolunteerAtopic Dermatitis
Regeneron Pharmaceuticals144 enrolled1 locationNCT07527923
Recruiting
Phase 1Phase 2
HL-300 Ointment in Patients With Mild-to-Moderate Atopic Dermatitis
Atopic Dermatitis
Hangzhou Highlightll Pharmaceutical Co., Ltd156 enrolled1 locationNCT07629778
Recruiting
Phase 1
Phase 1a/1b Study of TRB-061 in Healthy Participants & Patients With Atopic Dermatitis
Moderate-to-severe Atopic Dermatitis
TRex Bio, Inc.115 enrolled15 locationsNCT06934252
Recruiting
Phase 1
Study of S-4321 in Participants With an Autoimmune or Immune-mediated Disease
Psoriatic Arthritis (PsA)Rheumatoid Arthritis (RA)Psoriasis (PsO)+3 more
Seismic Therapeutic AU Pty Ltd24 enrolled2 locationsNCT07455578
Recruiting
Phase 1
Ph 1a/1b Single Ascending Dose and Multiple Ascending Dose Study of ARQ-234
EczemaAtopic Dermatitis (AD)
Arcutis Biotherapeutics, Inc.125 enrolled1 locationNCT07453602
Recruiting
Phase 1
A Phase 1 Clinical Study Comparing GS101 and Dupixent® After Subcutaneous Injection
Atopic Dermatitis (AD)
Jiangsu Genscend Biopharmaceutical Co., Ltd294 enrolled1 locationNCT07411755
Recruiting
Phase 1
A Study of SKB575 (HBM7575) Injection in Healthy Participants and Atopic Dermatitis Participants
Atopic Dermatitis
Sichuan Kelun-Biotech Biopharmaceutical Co., Ltd.90 enrolled2 locationsNCT07488065
Recruiting
Phase 1
The Impact of Botox on Neuroimmune Interactions in Atopic Dermatitis
Atopic Dermatitis (AD)
Daniel Kaplan8 enrolled2 locationsNCT06928246
Recruiting
Phase 1
A 3-part Study of SYX-5219 in Healthy Volunteers and Participants With Atopic Dermatitis
Moderate-to-severe Atopic Dermatitis
Sitryx Therapeutics Ltd149 enrolled14 locationsNCT07558668
Recruiting
Phase 1
A Study to Evaluate the Safety, Tolerability, Pharmacokinetics, and Pharmacodynamics of Single- and Multiple-Ascending Doses and Food Effect of BGB-45035 in Healthy Participants and in Adults With Autoimmune Dermatological Diseases
healthy adult participantsHealthy ParticipantsHealthy Volunteers+4 more
BeiGene211 enrolled13 locationsNCT06342713
Recruiting
Phase 1
Clinical Evaluation of Skin Microbiome an Over-The-Counter (OTC) Drug for Atopic Dermatitis
Atopic Dermatitis (AD)
Good Molecules, LLC36 enrolled1 locationNCT07146971
Recruiting
Phase 1
A Study to Compare the Pharmacokinetics, Pharmacodynamic, Immunogenicity, and Safety of CKD-706 With US-Dupixent®, and EU-Dupixent® in Healthy Adult Participants.
Atopic Dermatitis
Chong Kun Dang Pharmaceutical519 enrolled2 locationsNCT07358156
Recruiting
Phase 1
Clinical Study to Evaluate the Safety, Pharmacokinetics and Efficacy of VC005 in Adolescent Subjects With Mild to Moderate Atopic Dermatitis
Atopic Dermatitis (AD)
Jiangsu vcare pharmaceutical technology co., LTD10 enrolled1 locationNCT07329101