Phase 1 Bacteria Clinical Trials
17 recruitingPhase 1
What is a Phase 1 trial?
Phase 1 trials test a new treatment in a small group of people for the first time. The primary goal is to evaluate safety, determine a safe dosage range, and identify side effects. These studies typically enroll 20 to 80 participants.
Showing 1–17 of 17 trials
Recruiting
Phase 1
Trial to Evaluate Safety and Immune Response of an Investigational Pneumococcal Vaccine in Adults Aged 50 To 64 Years
Pneumonia, Bacterial
GlaxoSmithKline120 enrolled2 locationsNCT07428759
Recruiting
Phase 1Phase 2
FMT for the Decolonization of Carbapenem-resistant Enterobacteriaceae
Enterobacteriaceae InfectionsMulti-antibiotic Resistance
Fondazione Policlinico Universitario Agostino Gemelli IRCCS52 enrolled1 locationNCT04759001
Recruiting
Phase 1
[18F]Fluoropropyl-Trimethoprim ([18F]F-TMP) PET/CT Imaging to Evaluate Biodistribution and Kinetics in Human Subjects
Bacterial Infections
University of Pennsylvania20 enrolled1 locationNCT04263792
Recruiting
Phase 1
A Study to Investigate Safety and Pharmacokinetics of Intravenous Cefiderocol/Xeruborbactam in Participants With Renal Impairment
Bacterial Infections
Qpex Biopharma, Inc.40 enrolled2 locationsNCT07104162
Recruiting
Phase 1
Phase I Study of Single/Multiple Ascending Doses of JKN2501 for Injection in Chinese Healthy Volunteers
Bacterial InfectionsRespiratory Tract InfectionsUrinary Tract Infections+1 more
Joincare Pharmaceutical Group Industry Co., Ltd66 enrolled1 locationNCT07207291
Recruiting
Phase 1
Pilot Feasibility Study of Fecal Microbiota Transplant for the Treatment of Small Intestinal Bacterial Overgrowth
Small Intestinal Bacterial Overgrowth
McMaster Children's Hospital20 enrolled2 locationsNCT05967871
Recruiting
Phase 1Phase 2
Vaginal Microbiota Transplant
Recurrent Bacterial Vaginosis
Douglas Kwon62 enrolled1 locationNCT04046900
Recruiting
Phase 1
Evaluating the Effect Of Rifaximin on the Gut Microbiota and Metabolome in SIBO Using CapScan®
Small Intestinal Bacterial Overgrowth
Envivo Bio Inc34 enrolled1 locationNCT06298409
Recruiting
Phase 1Phase 2
Herbal Evaluation Of Artemisia Annua For Small Intestinal Bacterial Overgrowth
Small Intestinal Bacterial Overgrowth Syndrome (SIBO)
National University of Natural Medicine32 enrolled1 locationNCT06721884
Recruiting
Phase 1Phase 2
FMT to Eradicate Intestinal Colonization by Carbapenem-resistant Enterobacteriaceae
Enterobacteriaceae InfectionsMulti-antibiotic Resistance
Fondazione Policlinico Universitario Agostino Gemelli IRCCS36 enrolled1 locationNCT05791396
Recruiting
Phase 1
Safety and Effectiveness of the PXL-Platinum 330 System for Corneal Cross-Linking
Bacterial KeratitisEctasia of CorneaKeratoconus, Unstable
Pacific Clear Vision Institute300 enrolled1 locationNCT03918408
Completed
Phase 1
An Open-Label Study to Evaluate the Systemic Pharmacokinetics and Bioavailability of Single and Multiple Doses of RECCE®327 Topical Gel Applied to Normal Intact Skin in Healthy Male and Female Participants
Acute Bacterial Skin and Skin Structure InfectionsDiabetic Foot Infections
Recce Pharmaceuticals LTD12 enrolled1 locationACTRN12624001277538
Recruiting
Phase 1
Absorption of Antibiotics With High Oral Bioavailability in Short-bowel Syndrome
Short Bowel SyndromeInfection, Bacterial
Central Hospital, Nancy, France10 enrolled1 locationNCT05302531
Completed
Phase 1
A study to evaluate the Safety, Tolerability, Pharmacokinetics and Food-Effect of MRX-5 Tablets in Healthy Adult Subjects
Non-Tuberculous MycobacteriumInfectious Bacterial disease
Shanghai MicuRx Pharmaceutical Co., Ltd.84 enrolled1 locationACTRN12623001121651
Completed
Phase 1
A Study of Clofazimine Inhalation Suspension (MNKD-101) in Healthy Volunteers
Pulmonary Nontuberculous Mycobacteria Infections
MannKind Corporation40 enrolled1 locationACTRN12621001702808
Completed
Phase 1
An Ascending-dose, Randomized, Placebo-controlled, Parallel, Double-blind, Single-dose, First-in-Human Study to Evaluate the Safety and Pharmacokinetics of RECCE®327 in Healthy Male Subjects
Serious/life-threatening bacterial infections
Recce Pharmaceuticals, Ltd.80 enrolled1 locationACTRN12621001313820
Not Yet Recruiting
Phase 1
A study to evaluate the Safety and Pharmacokinetics (Pharmacokintecus, the measure of how the human body processes a substance) of ETX0282 when administered orally to healthy participants.
Enterobacteriaceae Infections
INC Research/ Inventiv Health116 enrolled1 locationACTRN12618000350224