Phase 1 Cholesterol Clinical Trials
13 recruitingPhase 1
What is a Phase 1 trial?
Phase 1 trials test a new treatment in a small group of people for the first time. The primary goal is to evaluate safety, determine a safe dosage range, and identify side effects. These studies typically enroll 20 to 80 participants.
Showing 1–13 of 13 trials
Recruiting
Phase 1
Phase 1b Study of VERVE-201 in Patients With Refractory Hyperlipidemia
HypercholesterolemiaHypertriglyceridemiaRefractory Hyperlipidemia
Verve Therapeutics, Inc.36 enrolled10 locationsNCT06451770
Recruiting
Phase 1
A Study of VERVE-102 in Patients With Familial Hypercholesterolemia or Premature Coronary Artery Disease
Premature Coronary Heart DiseaseHeterozygous Familial Hypercholesterolemia
Verve Therapeutics, Inc.85 enrolled22 locationsNCT06164730
Recruiting
Phase 1
Phase 1a Study to Evaluate the Safety, Tolerability, Pharmacokinetics, and Pharmacodynamics of RN5681 in Healthy Volunteers
High Cholesterol
Ikaria Bioscience Pty Ltd60 enrolled2 locationsNCT07347678
Recruiting
Phase 1
A Safety and Tolerability Trial Evaluating CTX310 in Participants With Refractory Dyslipidemias
HypercholesterolaemiaMetabolic DiseaseDyslipidemias+7 more
CRISPR Therapeutics AG90 enrolled18 locationsNCT07491172
Recruiting
Phase 1
Liver Adiposity Effects on Pediatric Statin
Cholesterol; Lipidosis
Children's Mercy Hospital Kansas City50 enrolled1 locationNCT04903223
Recruiting
Phase 1
A Study to Compare PK Characteristics and Safety Profiles Between AD-228B and AD-2284
Primary Hypercholesterolaemia
Addpharma Inc.60 enrolled1 locationNCT06884098
Terminated
Phase 1
A Study to Evaluate SGB-3403 in Healthy Volunteers
Hypercholesterolemia
Sanegene Bio Australia Pty Ltd37 enrolled1 locationACTRN12623000439640
Completed
Phase 1
A Study to Evaluate BW-00112 in Adult Subjects
Elevated Low-density lipoprotein cholesterol
ARGO BIOPHARMA AUSTRALIA PTY LTD32 enrolled1 locationACTRN12622001429741
Not Yet Recruiting
Phase 1
Supplementation of Oil Palm Phenolics in Healthy Subjects
HypercholesterolemiaHyperlipidaemia
Economic Planning Unit. Prime Minister’s Department. Malaysia100 enrolled1 locationACTRN12619001786189
Completed
Phase 1
A human trial to evaluate the performance and safety of a new formulation containing a cholesterol-lowering drug to healthy male volunteers.
Hypercholesterolemia
Reform Pharm Pty Ltd14 enrolled1 locationACTRN12618001929291
Completed
Phase 1
Comparative assessment of the absorption of a generic formulation of atorvastatin oral spray against the innovator atorvastatin capsule conducted under fasting conditions in healthy male and female volunteers
Pilot pharmacokinetic study conducted in healthy volunteers comparing two formulations of atorvastatin (oral spray and capsule) with no health condition or problem studied.
Although this study is being conducted in healthy volunteers who are not being treated for the condition to which the medicine is used, atorvastatin is used as an adjunct to diet for the treatment of patients with hypercholesterolaemia.
Zenith Technology Corp Ltd10 enrolled1 locationACTRN12618000208202
Recruiting
Phase 1
Effect of Fucoidan on glucose control and markers of cardiometabolic health after chronic dosing
Insulin Resistance/sensitivityHypercholesterolaemiaObesity+3 more
University of Tasmania.80 enrolled1 locationACTRN12614000495628
Completed
Phase 1
Palm Fruit Juice Supplementation in Healthy Volunteers
Pre-diabetesHypercholesterolemia
Malaysian Ministry of Agriculture & Agrobased industry25 enrolled1 locationACTRN12611001122943