Cruciate Ligament Reconstruction Clinical Trials

1 recruiting

Cruciate Ligament Reconstruction Trials at a Glance

15 actively recruiting trials for cruciate ligament reconstruction are listed on ClinicalTrialsFinder across 6 cities in 10 countries. The largest study group is Not Applicable with 9 trials, with the heaviest enrollment activity in Veranópolis, Valencia, and Chapel Hill. Lead sponsors running cruciate ligament reconstruction studies include Federal University of Health Science of Porto Alegre, Fundación Universidad Católica de Valencia San Vicente Mártir, and Arcadia University.

Browse cruciate ligament reconstruction trials by phase

Treatments under study

About Cruciate Ligament Reconstruction Clinical Trials

Looking for clinical trials for Cruciate Ligament Reconstruction? There are currently 1 studies actively recruiting participants. Clinical trials offer access to new treatments before they are widely available, and every approved therapy in use today was first tested through a clinical trial.

Below you can browse trials, sign up for alerts when new Cruciate Ligament Reconstruction trials open, and view eligibility criteria for each study. Each listing includes the study phase, locations, and enrollment details.

Frequently Asked Questions

Common questions about Cruciate Ligament Reconstruction clinical trials

A clinical trial is a carefully designed research study that tests new medical treatments, drugs, devices, or approaches in human volunteers. Every approved medication and treatment available today was proven safe and effective through clinical trials.

All clinical trials are reviewed and approved by Institutional Review Boards (IRBs) — independent committees that evaluate patient safety. Trials follow strict protocols, and your health is monitored closely throughout. You can withdraw at any time.

Not necessarily. Many trials compare the new treatment against the current standard of care, meaning all participants receive active treatment. When placebos are used, they are typically combined with standard treatment, not given alone. The trial description will always specify the design.

Under the Affordable Care Act, most private insurers are required to cover routine patient care costs during a clinical trial. The sponsor typically covers the investigational treatment itself. Medicare also covers routine costs for qualifying trials.

Yes. Participation is completely voluntary. You can withdraw at any time, for any reason, without it affecting your access to standard medical care.

Each trial has specific eligibility criteria — including age, diagnosis, disease stage, prior treatments, and general health. Browse the trials listed above and check their eligibility sections. You can also contact the trial site directly to discuss your situation.

Showing 115 of 15 trials

Recruiting

Effect of Graft Type on Knee Muscle Strength After ACL Reconstruction

Anterior Cruciate Ligament Reconstruction RehabilitationAnterior Cruciate Ligament (ACL) Reconstruction SurgeryStrength Outcomes
Hacettepe University80 enrolled1 locationNCT07523854
Recruiting
Not Applicable

Validating the Speckle Tracking Methods on Soft Tissue Strain, Displacement, and Roles in Physical Therapy

Anterior Cruciate Ligament Reconstruction RehabilitationUltrasound EvaluationUlnar Collateral Ligament Sprain+1 more
National Taiwan University Hospital80 enrolled1 locationNCT07485530
Recruiting
Not Applicable

Effectiveness of Blood Flow Restriction in Postoperative Rehabilitation for Anterior Cruciate Ligament Injuries. A Pilot Study.

Anterior Cruciate Ligament Reconstruction Rehabilitation
University of Valencia40 enrolled1 locationNCT06762392
Recruiting
Not Applicable

Comparison of Tendon and Muscle-Tendon Semitendinosus Grafts After ACL Reconstruction

Cruciate Ligament Reconstruction
University Hospital Dubrava40 enrolled1 locationNCT07404046
Recruiting
Not Applicable

ACL Reconstruction Rehabilitation With Exercise and Psychological Support

Anterior Cruciate Ligament Reconstruction Rehabilitation
HealthPartners Institute60 enrolled1 locationNCT06991192
Recruiting
Not Applicable

Effects of tDCS on Motor Cortex During ACL Recovery

Anterior Cruciate Ligament Reconstruction Rehabilitation
Fundación Universidad Católica de Valencia San Vicente Mártir54 enrolled1 locationNCT06818201
Recruiting
Not Applicable

Anterior Cruciate Ligaments: Studying Updates in neuroCognition After Knee Manipulation

Anterior Cruciate Ligament (ACL) TearAnterior Cruciate Ligament Reconstruction Rehabilitation
University of North Carolina, Chapel Hill30 enrolled1 locationNCT07058467
Recruiting
Phase 1Phase 2

Determining the Effects of Non-invasive Brain Stimulation to Improve Quadriceps Muscle Function After ACL Reconstruction

Anterior Cruciate Ligament Reconstruction RehabilitationQuadriceps Muscle Function
Arcadia University42 enrolled1 locationNCT07128602
Recruiting
Not Applicable

Evaluation of Home-based Telerehabilitation Platform to Augment Orthopedic Rehabilitation

Anterior Cruciate Ligament Reconstruction Rehabilitation
University of Mississippi Medical Center15 enrolled1 locationNCT06973642
Recruiting
Not Applicable

Effects of Eccentric Training in the Rehabilitation of Patients Undergoing Anterior Cruciate Ligament Reconstruction: a Randomized Controlled Trial

Anterior Cruciate Ligament Reconstruction Rehabilitation
Federal University of Health Science of Porto Alegre34 enrolled2 locationsNCT06905691
Recruiting
Not Applicable

Neuromuscular Electrical Stimulation Superimposed or Not on Voluntary Contraction After Reconstruction of the Anterior Cruciate Ligament: a Randomized Controlled Trial

Anterior Cruciate Ligament Reconstruction Rehabilitation
Federal University of Health Science of Porto Alegre40 enrolled2 locationsNCT06259968
Recruiting

Effect of Upper Limb Isometric Training on Hamstring Strength after Anterior Cruciate Ligament Reconstruction

Anterior Cruciate Ligament Reconstruction (ACLR)
Hospital Canselor Tuanku Muhriz UKM32 enrolled1 locationACTRN12624001445561
Recruiting

Integrated versus traditional rehabilitation program after anterior cruciate ligament (ACL) reconstruction in high level athletes

Anterior cruciate ligament reconstruction
University of L'Aquila40 enrolled1 locationACTRN12622000325707
Recruiting

Application of High Tone Power Therapy in patients after Anterior Cruciate Ligament reconstruction

Anterior cruciate ligament reconstruction
University of Physical Education in Krakow50 enrolled1 locationACTRN12616001416482
Recruiting
Phase 1

An evaluation of knee stability and functions following ACL reconstruction (semitendinosus/gracillis grafts) comparing manually versus mechanically tensioned grafts (using a tensioning device).

Knees requiring ACL-Anterior Cruciate Ligament reconstruction
Queensland Health50 enrolled1 locationACTRN12606000389505