Phase 4 CT Clinical Trials

866 recruitingPhase 4

What is a Phase 4 trial?

Phase 4 trials, also called post-marketing studies, are conducted after a treatment has been approved and is available to the public. They monitor long-term effectiveness and safety in a broader population.

Showing 120 of 866 trials

Recruiting
Phase 4

A Study to Evaluate the Effectiveness of Valbenazine in Adult Participants With Tardive Dyskinesia (TD) Who Remain Symptomatic While Receiving or After Stopping a Vesicular Monoamine Transporter 2 (VMAT2) Inhibitor

SchizophreniaMajor Depressive DisorderBipolar Disorder+2 more
Neurocrine Biosciences50 enrolled22 locationsNCT07105111
Recruiting
Phase 4

SIS-Reinforced vs. Conventional Anastomosis for Mid-to-Low Rectal Cancer: A Multicenter RCT on Anastomotic Leak

Rectal Cancer
Beijing Chao Yang Hospital966 enrolled1 locationNCT07209787
Recruiting
Phase 4

Allergy Delabeling in Antibiotic Stewardship - Intervention

Hematologic MalignancyBeta Lactam Allergy
Abramson Cancer Center at Penn Medicine3,800 enrolled1 locationNCT07133074
Recruiting
Phase 4

PRP vs PRP+Betamethasone vs Betamethasone Injection for Upper Trapezius Myofascial Pain

Trigger Point in Trapezius MuscleMyofascial Pain Dysfunction SyndromeTrigger Points, Myofascial
University of Kyrenia150 enrolled2 locationsNCT07547605
Recruiting
Phase 4

Opioid Free Anesthesia-Analgesia Strategy and Surgical Stress in Elective Open Abdominal Aortic Aneurysm Repair

Opioid UsePostoperative PainAnesthesia+5 more
University of Crete40 enrolled1 locationNCT04894864
Recruiting
Phase 4

A Study to Investigate Airway Inflammation With Dupilumab Subcutaneously in Participants Aged ≥40 to ≤85 Years With Chronic Obstructive Pulmonary Disease.

Chronic Obstructive Pulmonary Disease
Sanofi218 enrolled68 locationsNCT07053423
Recruiting
Phase 4

Optimization of Beta-lactam Dosing in Critically Ill Patients With Cystatin C (OPTIMIZE-GNI)

Bacterial infection
National Institute of Allergy and Infectious Diseases (NIAID)200 enrolled10 locationsNCT06709521
Recruiting
Phase 4

Morning Versus Afternoon Administration of Immunotherapy for the Treatment of Advanced or Metastatic Solid Tumors, The Knight SHIFT Study

Metastatic Head and Neck Squamous Cell CarcinomaMetastatic Hepatocellular CarcinomaMetastatic Lung Non-Small Cell Carcinoma+18 more
OHSU Knight Cancer Institute160 enrolled1 locationNCT07405086
Recruiting
Phase 4

L-Citrulline and Tadalafil for Mild to Moderate Erectile Dysfunction

Erectile Dysfunction
Beni-Suef University133 enrolled1 locationNCT07642505
Recruiting
Phase 4

The Basel BOMP-AID Randomized Trial

Hypoactive Delirium
University Hospital, Basel, Switzerland190 enrolled1 locationNCT03438526
Recruiting
Phase 4

A Study to Provide Continued Access to Study Drug to Children and Adolescents Who Have Completed Clinical Studies Involving Gilead HIV Treatments

HIV-1-infection
Gilead Sciences350 enrolled15 locationsNCT06337032
Recruiting
Phase 4

The Effect of Rifabutin in Mycobacterium Abscessus With Inducible Clarithromycin Resistance

Mycobacterium Abscessus Lung Disease
National Taiwan University Hospital60 enrolled1 locationNCT07514364
Recruiting
Phase 4

Trial of an AI-enabled Digital Stethoscope to Improve Antibiotic Stewardship

Respiratory Infections in Children
Johns Hopkins University2,500 enrolled1 locationNCT07362433
Recruiting
Phase 4

Study to Evaluate a New Cartilage Regeneration Platform for Knee Cartilage Repair

Cartilage Defects of the Knee
ROKIT Healthcare104 enrolled13 locationsNCT07639424
Recruiting
Phase 4

Efficacy of Vevye Ophthalmic Solution for the Treatment of Meibomian Gland Dysfunction

Meibomian Gland Dysfunction (MGD)
University of Alabama at Birmingham48 enrolled1 locationNCT07224529
Recruiting
Phase 4

Study of Efficacy and Safety of Ruxolitinib in Chinese Participants With Corticosteroid-refractory Chronic Graft vs. Host Disease

Graft vs Host DiseaseChronic Graft vs. Host DiseaseCorticosteroid-refractory Chronic Graft vs. Host Disease
Novartis Pharmaceuticals50 enrolled22 locationsNCT06824103
Recruiting
Phase 4

Rice-derived Recombinant Human Serum Albumin for the Treatment of Hypoalbuminemia After Hepatectomy: A Prospective, Single-Arm, Exploratory Clinical Trial

Post-hepatectomy Hypoalbuminemia
Cheng Qi50 enrolled1 locationNCT07634549
Recruiting
Phase 4

Colchicine's Effect on Inflammatory Markers

ColchicinePost-operative Atrial FibrillationInflammation in Cardiac Surgery+2 more
Ayesha Ather24 enrolled1 locationNCT07287345
Recruiting
Phase 4

Cervicothoracic Sympathetic Block Evaluation for Post COVID Condition

Autonomic Dysfunction
University Health Network, Toronto78 enrolled3 locationsNCT07468604
Recruiting
Phase 4

Stroke Prevention In Ischemic Stroke With Covert Atrial Fibrillation

Atrial FibrillationStrokeIschemic Stroke+1 more
Assistance Publique - Hôpitaux de Paris1,148 enrolled1 locationNCT06486792