Phase 3 Cutaneous Clinical Trials
21 recruitingPhase 3
What is a Phase 3 trial?
Phase 3 trials compare the new treatment against the current standard of care in large groups, often hundreds to thousands of participants. Successful Phase 3 results are typically required for regulatory approval.
Showing 1–20 of 21 trials
Recruiting
Phase 3
Testing the Addition of an Immunotherapy Drug, Cemiplimab (REGN2810), Plus Surgery to the Usual Surgery Alone for Treating Advanced Skin Cancer
Stage III Head and Neck Cutaneous Squamous Cell Carcinoma AJCC v8Stage IV Head and Neck Cutaneous Squamous Cell Carcinoma AJCC v8Eyelid Squamous Cell Carcinoma+17 more
National Cancer Institute (NCI)420 enrolled206 locationsNCT06568172
Recruiting
Phase 3
Testing the Addition of Anti-Cancer Drug, Cetuximab, to Standard of Care Treatment (Pembrolizumab) for Returning or Spreading Head and Neck Cancer After Previous Treatment
Metastatic Head and Neck Squamous Cell CarcinomaStage IV Head and Neck Cutaneous Squamous Cell Carcinoma AJCC v8Recurrent Head and Neck Squamous Cell Carcinoma+18 more
National Cancer Institute (NCI)158 enrolled176 locationsNCT06589804
Recruiting
Phase 3
A Study of Enpatoran in Participants With Cutaneous Manifestations of Lupus With or Without Systemic Disease
Systemic Lupus Erythematosus (SLE)Cutaneous Lupus Erythematosus (CLE)
EMD Serono Research & Development Institute, Inc.202 enrolled3 locationsNCT07332481
Recruiting
Phase 2Phase 3
A 2-Part Study to Learn Whether Litifilimab (BIIB059) Injections Can Improve Symptoms of Adult Participants Who Have Active Cutaneous Lupus Erythematosus
Subacute Cutaneous Lupus ErythematosusChronic Cutaneous Lupus Erythematosus
Biogen450 enrolled314 locationsNCT05531565
Recruiting
Phase 3
A Study of Enpatoran in Participants With Cutaneous Manifestations of Lupus With or Without Systemic Disease (ELOWEN-2)
Cutaneous Lupus ErythematosusSystematic Lupus Erythematosus
EMD Serono Research & Development Institute, Inc.202 enrolled3 locationsNCT07355218
Recruiting
Phase 3
Study of Intralesional Cemiplimab in Adult Patients With Early Stage Cutaneous Squamous Cell Carcinoma
Cutaneous Squamous Cell Carcinoma (CSCC)
Regeneron Pharmaceuticals369 enrolled49 locationsNCT06585410
Recruiting
Phase 3
Study of a Strategy Integrating Adjuvant Radiation Therapy Versus Strategy Based on Monitoring in the Treatment of Carcinomas Spinocellular With High Risk of Recurrence
Cutaneous Squamous Cell Carcinoma (CSCC)
Centre Leon Berard266 enrolled28 locationsNCT06692556
Recruiting
Phase 3
SUPRAME-ACTengine® IMA203 vs. Investigator's Choice of Treatment in Previously Treated, Unresectable or Metastatic Cutaneous Melanoma
Melanoma, Cutaneous Malignant
Immatics US, Inc.360 enrolled59 locationsNCT06743126
Recruiting
Phase 2Phase 3
A Trial of LNS8801 With or Without Pembrolizumab in Patients With Refractory Melanoma
Unresectable MelanomaCutaneous MelanomaMelanoma (Skin Cancer)+1 more
Linnaeus Therapeutics, Inc.135 enrolled9 locationsNCT06624644
Recruiting
Phase 3
High-dose Prophylactic Gabapentin (HOPE) vs. Placebo to Prevent Opioid Use for Oral Mucositis Pain During Concurrent Chemoradiation for Head and Neck Cancer
Head and Neck Squamous Cell CarcinomaStage III Head and Neck Cutaneous Squamous Cell Carcinoma AJCC v8Stage IV Head and Neck Cutaneous Squamous Cell Carcinoma AJCC v8+2 more
Alliance for Clinical Trials in Oncology228 enrolled187 locationsNCT06992427
Recruiting
Phase 3
Confirmatory Study of Topical HyBryte™ vs. Placebo for the Treatment of CTCL
Mycosis FungoidesCutaneous T Cell LymphomaCTCL+1 more
Soligenix80 enrolled17 locationsNCT06470451
Recruiting
Phase 3
Arnica Tincture Fot the Treatment of Cutaneous Leishmaniasis II.
Leishmaniasis, Cutaneous
Universidad de Antioquia96 enrolled1 locationNCT06822478
Recruiting
Phase 3
A Phase III Study to Investigate the Efficacy and Safety of Anifrolumab in Adults With Chronic and/or Subacute Cutaneous Lupus Erythematosus
Cutaneous Lupus Erythematosus
AstraZeneca302 enrolled272 locationsNCT06015737
Recruiting
Phase 3
Adding Dexmedetomidine or Tramadol to Paracetamol- An Effort to Attenuate Catheter Related Bladder Discomfort
Percutaneous Nephrolithotripsy (PCNL)
Al-Azhar University60 enrolled1 locationNCT06274333
Recruiting
Phase 2Phase 3
Remote Ischemic Preconditioning for Renal and Cardiac Protection in Congestive Heart Failure (RICH) Trial
Heart FailureAcute Kidney InjuryPercutaneous Coronary Intervention+2 more
VA Office of Research and Development240 enrolled3 locationsNCT04982419
Recruiting
Phase 3
Randomised Clinical Trial for New Treatment Modalities for Cutaneous Leishmaniasis Caused by Leishmania Tropica, in Pakistan
Old World Cutaneous Leishmaniasis
Medecins Sans Frontieres, Netherlands832 enrolled2 locationsNCT04268524
Recruiting
Phase 3
Safety and Efficacy of Baricitinib on Skin Tightening in Diffuse Cutaneous Systemic Sclerosis: A Comparative Study With Methotrexate
Diffuse Cutaneous Systemic Sclerosis
Bangabandhu Sheikh Mujib Medical University, Dhaka, Bangladesh24 enrolled1 locationNCT06936215
Recruiting
Phase 3
Efficacy and Safety of Colchicine After PCI
Coronary Heart DiseasePercutaneous Coronary InterventionColchicine
Union Hospital, Tongji Medical College, Huazhong University of Science and Technology8,862 enrolled36 locationsNCT06472908
Recruiting
Phase 3
Efficacy and Safety Study of Vicagrel in Patients With Acute Coronary Syndrome (ACS) Undergoing Percutaneous Coronary Intervention (PCI)
Acute Coronary Syndrome (ACS) Undergoing Percutaneous Coronary Intervention (PCI)
Jiangsu vcare pharmaceutical technology co., LTD1,000 enrolled1 locationNCT06577519
Recruiting
Phase 2Phase 3
Pilot Study: Oral Treatment of American Tegumentary Leishmaniasis (Cutaneous and Mucosal Forms) in the Elderly
Leishmaniasis, MucocutaneousLeishmaniasis; Brazilian
University of Brasilia100 enrolled1 locationNCT06040489