Deep Caries Clinical Trials

7 recruitingLast updated: July 25, 2026

There are 7 actively recruiting deep caries clinical trials across 4 countries. Studies span Not Applicable, Phase 2, Phase 4. Top locations include Rohtak, Haryana, India, Cairo, Egypt, Espoo, Finland. Updated daily from ClinicalTrials.gov.


Deep Caries Trials at a Glance

7 actively recruiting trials for deep caries are listed on ClinicalTrialsFinder across 4 cities in 4 countries. The largest study group is Not Applicable with 4 trials, with the heaviest enrollment activity in Rohtak, Cairo, and Espoo. Lead sponsors running deep caries studies include Postgraduate Institute of Dental Sciences Rohtak, Cairo University, and National University Hospital, Singapore.

Browse deep caries trials by phase

Treatments under study

About Deep Caries Clinical Trials

Looking for clinical trials for Deep Caries? There are currently 4 studies actively recruiting participants. Clinical trials offer access to new treatments before they are widely available, and every approved therapy in use today was first tested through a clinical trial.

Below you can browse trials, sign up for alerts when new Deep Caries trials open, and view eligibility criteria for each study. Each listing includes the study phase, locations, and enrollment details.

Frequently Asked Questions

Common questions about Deep Caries clinical trials

A clinical trial is a carefully designed research study that tests new medical treatments, drugs, devices, or approaches in human volunteers. Every approved medication and treatment available today was proven safe and effective through clinical trials.

All clinical trials are reviewed and approved by Institutional Review Boards (IRBs) — independent committees that evaluate patient safety. Trials follow strict protocols, and your health is monitored closely throughout. You can withdraw at any time.

Not necessarily. Many trials compare the new treatment against the current standard of care, meaning all participants receive active treatment. When placebos are used, they are typically combined with standard treatment, not given alone. The trial description will always specify the design.

Under the Affordable Care Act, most private insurers are required to cover routine patient care costs during a clinical trial. The sponsor typically covers the investigational treatment itself. Medicare also covers routine costs for qualifying trials.

Yes. Participation is completely voluntary. You can withdraw at any time, for any reason, without it affecting your access to standard medical care.

Each trial has specific eligibility criteria — including age, diagnosis, disease stage, prior treatments, and general health. Browse the trials listed above and check their eligibility sections. You can also contact the trial site directly to discuss your situation.

Showing 17 of 7 trials

Recruiting
Not Applicable

Comparative Evaluation of Direct Pulp Capping Between Deep and Extremely Deep Caries in Mature Permanent Mandibular Molars With Reversible Pulpitis

Reversible PulpitisExtremely Deep CariesDeep Caries
Postgraduate Institute of Dental Sciences Rohtak130 enrolled1 locationNCT07696702
Recruiting
Not Applicable

Influence of Proximal Caries on Outcome of Direct Pulp Capping in Permanent Mandibular Molars With Reversible Pulpitis

Reversible PulpitisExtremely Deep Caries
Postgraduate Institute of Dental Sciences Rohtak154 enrolled1 locationNCT07578662
Recruiting

The Prognostic Impact of Symptoms and Lesion Depth in Partial Removal of Carious Tissue

Deep CariesPulpitis ReversiblePulp Hyperemia
University of Helsinki100 enrolled1 locationNCT05816525
Recruiting
Phase 4

Comparison Between Egyptian MTA, Biodentine Versus Calcium Hydroxide as Indirect Pulp Capping Materials In Permanent Teeth

Patient Reported Outcome MeasuresCalcium HydroxideDeep Caries+3 more
Cairo University35 enrolled1 locationNCT06683833
Recruiting
Phase 2

Clinical and Radiographic Success Rate of Pulpotomy Versus Pulpectomy for Management of Primary Teeth With Deep Caries

Deep Caries
Cairo University40 enrolled1 locationNCT06293521
Recruiting
Not Applicable

Effectiveness of Pulpotomy vs. Root Canal Treatment in Extremely Deep Caries

PulpitisExtremely Deep Caries
National University Hospital, Singapore93 enrolled1 locationNCT07242742
Recruiting
Not Applicable

Outcome of Partial Pulpotomy in Moderate and Severe Pulpitis

Moderate PulpitisSevere PulpitisExtremely Deep Caries
Postgraduate Institute of Dental Sciences Rohtak120 enrolled1 locationNCT07123025