Phase 1 DIGEST Clinical Trials
9 recruitingPhase 1
What is a Phase 1 trial?
Phase 1 trials test a new treatment in a small group of people for the first time. The primary goal is to evaluate safety, determine a safe dosage range, and identify side effects. These studies typically enroll 20 to 80 participants.
Showing 1–9 of 9 trials
Recruiting
Phase 1
First-in-human Study of IDRX-42 in Participants With Metastatic and/or Unresectable Gastrointestinal Stromal Tumors
Metastatic CancerGastrointestinal NeoplasmsGastrointestinal Diseases+2 more
IDRX, Inc., a wholly owned subsidiary of GSK, LLC278 enrolled31 locationsNCT05489237
Recruiting
Phase 1Phase 2
A Study of BL-M07D1 in Patients With a Variety of Solid Tumors Including Locally Advanced or Metastatic HER2-positive/Low-expressing Urinary and Gastrointestinal Tumors
Her2-positive/Low-expression Urinary and Digestive Tract Tumors
Sichuan Baili Pharmaceutical Co., Ltd.42 enrolled1 locationNCT06031584
Recruiting
Phase 1
Combination External Radiation and PRRT for Large GI Neuroendocrine Tumors.
Digestive System Neuroendocrine TumorUnresectable Digestive System Neuroendocrine NeoplasmUnresectable Digestive System Neuroendocrine Tumor G1+1 more
Emory University15 enrolled2 locationsNCT07150546
Recruiting
Phase 1
Phase I Clinical Study of BL-M07D1 in Locally Advanced or Metastatic Digestive Tract Tumors and Other Solid Tumors
Other Solid TumorsLocally Advanced or Metastatic Digestive Tract Tumors
Sichuan Baili Pharmaceutical Co., Ltd.26 enrolled1 locationNCT05631964
Recruiting
Phase 1Phase 2
To Evaluate KC1036 in the Patients with Advanced Digestive System Tumors
Digestive System Tumors
Beijing Konruns Pharmaceutical Co., Ltd.133 enrolled13 locationsNCT05260385
Recruiting
Phase 1
A Trial to Evaluate the Safety, Tolerability, Pharmacokinetics and Preliminary Efficacy of DR30303 in Patients With Advanced Solid Tumors
Malignant Neoplasm of Digestive System
Zhejiang Doer Biologics Co., Ltd.94 enrolled1 locationNCT05639153
Recruiting
Phase 1
Clinical Study of Personalized mRNA Vaccine Encoding Neoantigen in Subjects With Resected Digestive System Neoplasms
Digestive System Neoplasms
Sir Run Run Shaw Hospital20 enrolled1 locationNCT06026774
Recruiting
Phase 1
Clinical Study of Personalized mRNA Vaccine Encoding Neoantigen Alone in Subjects With Advanced Digestive System Neoplasms
Digestive System Neoplasms
Sir Run Run Shaw Hospital20 enrolled1 locationNCT06019702
Recruiting
Phase 1
Clinical Study of Personalized mRNA Vaccine Encoding Neoantigen in Combination With Standard First-line Treatment in Subjects With Advanced Digestive System Neoplasms
Digestive System Neoplasms
Sir Run Run Shaw Hospital20 enrolled1 locationNCT06026800