Eosinophilic Esophagitis (EoE) Clinical Trials

8 recruitingLast updated: June 18, 2026

There are 8 actively recruiting eosinophilic esophagitis (eoe) clinical trials across 3 countries. Studies span Not Applicable, Phase 3, Phase 4. Top locations include Philadelphia, Pennsylvania, United States, Aurora, Colorado, United States, Boston, Massachusetts, United States. Updated daily from ClinicalTrials.gov.


Eosinophilic Esophagitis (EoE) Trials at a Glance

8 actively recruiting trials for eosinophilic esophagitis (eoe) are listed on ClinicalTrialsFinder across 6 cities in 3 countries. The largest study group is Not Applicable with 1 trial, with the heaviest enrollment activity in Philadelphia, Aurora, and Boston. Lead sponsors running eosinophilic esophagitis (eoe) studies include Regeneron Pharmaceuticals, Fondazione IRCCS Policlinico San Matteo di Pavia, and Children's Hospital of Philadelphia.

Browse eosinophilic esophagitis (eoe) trials by phase

Treatments under study

About Eosinophilic Esophagitis (EoE) Clinical Trials

Looking for clinical trials for Eosinophilic Esophagitis (EoE)? There are currently 8 studies actively recruiting participants. Clinical trials offer access to new treatments before they are widely available, and every approved therapy in use today was first tested through a clinical trial.

Below you can browse trials, sign up for alerts when new Eosinophilic Esophagitis (EoE) trials open, and view eligibility criteria for each study. Each listing includes the study phase, locations, and enrollment details.

Frequently Asked Questions

Common questions about Eosinophilic Esophagitis (EoE) clinical trials

A clinical trial is a carefully designed research study that tests new medical treatments, drugs, devices, or approaches in human volunteers. Every approved medication and treatment available today was proven safe and effective through clinical trials.

All clinical trials are reviewed and approved by Institutional Review Boards (IRBs) — independent committees that evaluate patient safety. Trials follow strict protocols, and your health is monitored closely throughout. You can withdraw at any time.

Not necessarily. Many trials compare the new treatment against the current standard of care, meaning all participants receive active treatment. When placebos are used, they are typically combined with standard treatment, not given alone. The trial description will always specify the design.

Under the Affordable Care Act, most private insurers are required to cover routine patient care costs during a clinical trial. The sponsor typically covers the investigational treatment itself. Medicare also covers routine costs for qualifying trials.

Yes. Participation is completely voluntary. You can withdraw at any time, for any reason, without it affecting your access to standard medical care.

Each trial has specific eligibility criteria — including age, diagnosis, disease stage, prior treatments, and general health. Browse the trials listed above and check their eligibility sections. You can also contact the trial site directly to discuss your situation.

Showing 18 of 8 trials

Recruiting

Natural History of Eosinophilic Esophagitis in Adult and Pediatric Population

Eosinophilic Esophagitis (EoE)
Fondazione IRCCS Policlinico San Matteo di Pavia200 enrolled2 locationsNCT07614633
Recruiting
Phase 3

A Study of Dupilumab in Small Children With an Allergic Condition of the Esophagus (Food Pipe): Eosinophilic Esophagitis

Eosinophilic Esophagitis (EoE)
Regeneron Pharmaceuticals20 enrolled10 locationsNCT07112378
Recruiting

A U.S. Registry of Eosinophilic Esophagitis Pediatric, Adolescent and Adult Patients Treated With DUPIXENT® As Standard of Care

Eosinophilic Esophagitis (EoE)
Regeneron Pharmaceuticals350 enrolled54 locationsNCT06693531
Recruiting
Not Applicable

Trial of Partial Enteral Nutrition With Dairy Free Diet in Eosinophilic Esophagitis

Eosinophilic Esophagitis (EoE)
Kate Farms Inc36 enrolled1 locationNCT07234825
Recruiting

Surface EMG Testing on Swallowing in EoE Patients

Eosinophilic Esophagitis (EoE)
Mayo Clinic30 enrolled1 locationNCT07156357
Recruiting

Local Clinical and Immunological Responses in Eosinophilic Esophagitis (EoE) Patients, Role of Mucosal Barrier Function and Type II Inflammation

Eosinophilic Esophagitis (EoE)
Academisch Medisch Centrum - Universiteit van Amsterdam (AMC-UvA)56 enrolled1 locationNCT07012928
Recruiting

Esophageal String Test Monitoring to Monitor Eosinophilic Esophagitis During Oral Immunotherapy

Eosinophilic Esophagitis (EoE)
Children's Hospital of Philadelphia75 enrolled1 locationNCT06389994
Recruiting
Phase 4

Effect of Dupilumab on the Muscle Function of the Esophagus (food Pipe) in Participants with Eosinophilic Esophagitis (EoE)

Eosinophilic Esophagitis (EoE)
University of California, San Diego30 enrolled1 locationNCT06665971