Phase 1 Exposure Clinical Trials

3 recruitingPhase 1

What is a Phase 1 trial?

Phase 1 trials test a new treatment in a small group of people for the first time. The primary goal is to evaluate safety, determine a safe dosage range, and identify side effects. These studies typically enroll 20 to 80 participants.

Showing 1–3 of 3 trials

Recruiting

Phase 1Phase 2

A Phase Ib/II Open-label Study of AMO959 With Lutetium (177Lu) Vipivotide Tetraxetan (AAA617) in Combination With ARPI in Adult Participants With PSMA-positive mCRPC

PSMA-positive Metastatic Castration Resistant Prostate Cancer (mCRPC) With Prior Exposure to One Prior ARPI Who Are Candidates for Taxane-based Chemotherapy

Novartis Pharmaceuticals123 enrolled11 locationsNCT07226986

Recruiting

Phase 1Phase 2

Examining a Novel Gastrointestinal Intervention to Negate Environmental Toxicants (ENGINE)

Toxicant ExposureFirefighterOccupational Exposure to Chemicals

University of California, San Francisco50 enrolled1 locationNCT07226440

Recruiting

Phase 1

Ph1, Randomized, Double-Blind and Controlled, Dose Escalation and Expansion Study to Assess the Safety and Pharmacokinetics of JST-010 in Healthy Adults

Pre-exposure Prophylaxis Against Pneumonic Plague in Healthy Adults

Just-Evotec Biologics104 enrolled1 locationNCT06943378