Phase 1 Fibromatosis Clinical Trials
6 recruitingPhase 1
What is a Phase 1 trial?
Phase 1 trials test a new treatment in a small group of people for the first time. The primary goal is to evaluate safety, determine a safe dosage range, and identify side effects. These studies typically enroll 20 to 80 participants.
Showing 1–6 of 6 trials
Recruiting
Phase 1Phase 2
Cyclin-Dependent Kinase (CDK)4/6 Inhibitor Abemaciclib for Neurofibromatosis Type I (NF1) Related Atypical Neurofibromas
Neurofibromatosis 1
National Cancer Institute (NCI)55 enrolled1 locationNCT04750928
Recruiting
Phase 1
Feasibility and Tolerability of IMLYGIC for the Treatment of Cutaneous Neurofibromas in Adults With NF1
NeurofibromatosisNF1Cutaneous Neurofibroma+3 more
Johns Hopkins University10 enrolled1 locationNCT07102394
Recruiting
Phase 1Phase 2
Tegavivint for the Treatment of Recurrent or Refractory Solid Tumors, Including Lymphomas and Desmoid Tumors
Ovarian CarcinomaColorectal CarcinomaMelanoma+19 more
Children's Oncology Group147 enrolled21 locationsNCT04851119
Recruiting
Phase 1Phase 2
A Phase I/II Study of Trametinib and Azacitidine for Patients With Newly Diagnosed Juvenile Myelomonocytic Leukemia
Neurofibromatosis 1Leukemia, Juvenile MyelomonocyticJMML+2 more
Therapeutic Advances in Childhood Leukemia Consortium58 enrolled19 locationsNCT05849662
Recruiting
Phase 1
PAS-004 in Adults Who Have Neurofibromatosis Type 1 With Plexiform Neurofibromas
NF1 MutationNeurofibroma, PlexiformNeurofibromatosis Type 1 (NF1)-Related Plexiform Neurofibromas (PNs)+1 more
Pasithea Therapeutics Corp.56 enrolled5 locationsNCT06961565
Completed
Phase 1
Pilot Study of Assistive Listening Devices in Treating Auditory Processing Deficits in Neurofibromatosis Type 1
auditory processing deficits in children with Neurofibromatosis Type 1
Murdoch Children's Research Institute10 enrolled1 locationACTRN12619000525189