Phase 2 Function Clinical Trials
111 recruitingPhase 2
What is a Phase 2 trial?
Phase 2 trials evaluate whether a treatment works for a specific condition and further assess its safety. These studies typically enroll several hundred participants and provide preliminary data on effectiveness.
Showing 1–20 of 111 trials
Recruiting
Phase 2
A Study of CS060380 Tablets in Patients With MASH and Obesity
Metabolic dysfunction-associated steatohepatitis (MASH)Obesity
Cascade Pharmaceuticals, Inc120 enrolled12 locationsNCT07466017
Recruiting
Phase 2
Tesamorelin as an Adjunct to Exercise for Improving Physical Function in HIV
FrailtyAgingHIV-1-infection+2 more
Massachusetts General Hospital100 enrolled2 locationsNCT06554717
Recruiting
Phase 2
LAM-001 in Lung Transplant Recipients With Bronchiolitis Obliterans Syndrome.
Bronchiolitis Obliterans SyndromeLung transplantationChronic lung allograft dysfunction
Steven Hays, MD30 enrolled1 locationNCT06018766
Recruiting
Phase 2
Hematopoietic Stem Cell Transplantation (HSCT) for Common Variable Immunodeficiency (CVID) and Other Autoimmune Manifestations of Primary Immune Regulatory Disorders (PIRD)
Immune DysregulationPrimary Immune Regulatory DisorderChronic Granulomatous Disease+12 more
Paul Szabolcs25 enrolled1 locationNCT07284641
Recruiting
Phase 2
Testing Lutetium Lu 177 Dotatate in Patients With Somatostatin Receptor Positive Advanced Bronchial Neuroendocrine Tumors
Lung Neuroendocrine NeoplasmAdvanced Lung Neuroendocrine TumorFunctioning Lung Neuroendocrine Tumor+9 more
National Cancer Institute (NCI)70 enrolled29 locationsNCT04665739
Recruiting
Phase 2Phase 3
Efficacy, Safety, and Pharmacokinetics of Vericiguat in Pediatric Participants With Heart Failure Due to Left Ventricular Systolic Dysfunction (MK-1242-036)
Heart FailureLeft Ventricular Systolic Dysfunction
Merck Sharp & Dohme LLC342 enrolled106 locationsNCT05714085
Recruiting
Phase 2
A Precision Medicine Approach Using Gene Silencing to Treat a Chronic Liver Disease Called Metabolic Dysfunction-Associated Steatohepatitis (MASH) in Adult Participants at Increased Genetic Risk for This Condition
Metabolic dysfunction-associated steatohepatitis (MASH)
Regeneron Pharmaceuticals120 enrolled71 locationsNCT05519475
Recruiting
Phase 2Phase 3
Effect of Amitriptyline and Trifluoperazine on Patients With Functional Dyspepsia
Functional Dyspepsia
Md. Moktadirul Hoque Shuvo120 enrolled1 locationNCT07008235
Recruiting
Phase 2
A Study to Evaluate the Use of Resmetirom in Participants With MASLD and HIV
HIV (Human Immunodeficiency Virus)MASLD - Metabolic Dysfunction-Associated Steatotic Liver Disease
Naga P. Chalasani120 enrolled10 locationsNCT07143968
Recruiting
Phase 1Phase 2
Enhancing Parasympathetic Activity to Improve Endothelial Dysfunction, Vascular Oxidative Stress in African Americans
Endothelial Dysfunction
Vanderbilt University Medical Center160 enrolled1 locationNCT04769206
Recruiting
Phase 2
Repurposing Valsartan May Protect Against Pulmonary Hypertension
Pulmonary Arterial HypertensionRight Ventricular DysfunctionRight Heart Failure+1 more
University of Washington60 enrolled1 locationNCT06053580
Recruiting
Phase 2
Investigation of the Efficacy of a Probiotic Mixture in Moderate Metabolic Dysfunction-Associated Steatotic Liver Disease (MASLD): A Mechanistic Trial
MASLD - Metabolic Dysfunction-Associated Steatotic Liver DiseaseFatty Liver Disease, NonalcoholicOverweight (BMI > 25)
AB Biotics, SA60 enrolled1 locationNCT07193927
Recruiting
Phase 2
Study to Evaluate Resmetirom in Post-Liver Transplant Patients With MASH
MASH - Metabolic Dysfunction-Associated Steatohepatitis
Madrigal Pharmaceuticals, Inc.120 enrolled15 locationsNCT07335601
Recruiting
Phase 1Phase 2
Cerebral Blood Flow and Ventilatory Responses During Sleep in Normoxia and Intermittent Hypoxia
Hypoxia, BrainBlood PressureStroke+5 more
University of Calgary12 enrolled1 locationNCT03255408
Recruiting
Phase 2
A Study to Investigate Mibavademab in Adult Women With Functional Hypothalamic Amenorrhea
Functional Hypothalamic Amenorrhea (FHA)
Regeneron Pharmaceuticals34 enrolled5 locationsNCT07235917
Recruiting
Phase 1Phase 2
A Study to Evaluate ALN-CIDEB in Adult Participants With Metabolic Dysfunction-Associated Steatotic Liver Disease or With Metabolic Dysfunction-Associated Steatohepatitis (MASLD/MASH)
Metabolic Dysfunction-Associated Steatotic Liver DiseaseMetabolic Dysfunction-Associated Steatohepatitis
Regeneron Pharmaceuticals132 enrolled3 locationsNCT06836609
Recruiting
Phase 1Phase 2
Safety and Efficacy of Treprostinil (Remodulin®) In Reducing Ischemia-Reperfusion Injury During Kidney Transplantation
Ischemia Reperfusion InjuryDelayed Graft Function
Rhode Island Hospital20 enrolled1 locationNCT04005469
Recruiting
Phase 2
A Digital Intervention for Post-Stroke Depression and Executive Dysfunction
DepressionStrokeExecutive Dysfunction
Weill Medical College of Cornell University70 enrolled1 locationNCT05507138
Recruiting
Phase 2
A Study of a Thyroid Hormone Receptor Beta Isoform (THRβ) Agonist and an Semicarbazide Sensitive Amine Oxidase (SSAO) Inhibitor, Alone and in Combination, in Adults With Presumed Metabolic Dysfunction-associated Steatohepatitis (MASH)
Metabolic Dysfunction-Associated Steatohepatitis
Eccogene160 enrolled53 locationsNCT07288138
Recruiting
Phase 1Phase 2
Stem Cell Therapy for Early Alzheimer's Disease
Cognitive Dysfunction
Paul E Schulz12 enrolled1 locationNCT06775964