Phase 2 Function Clinical Trials
121 recruitingPhase 2
What is a Phase 2 trial?
Phase 2 trials evaluate whether a treatment works for a specific condition and further assess its safety. These studies typically enroll several hundred participants and provide preliminary data on effectiveness.
Showing 1–20 of 121 trials
Recruiting
Phase 2
A Study of Donanemab (LY3002813) in Participants With Early Cognitive Decline (TRAILBLAZER-ALZ 7)
Cognitive DysfunctionLewy Body DiseaseAmyloid+1 more
Eli Lilly and Company350 enrolled72 locationsNCT07589595
Recruiting
Phase 2
A Study of a Thyroid Hormone Receptor Beta Isoform (THRβ) Agonist and an Semicarbazide Sensitive Amine Oxidase (SSAO) Inhibitor, Alone and in Combination, in Adults With Presumed Metabolic Dysfunction-associated Steatohepatitis (MASH)
Metabolic Dysfunction-Associated Steatohepatitis
Eccogene160 enrolled62 locationsNCT07288138
Recruiting
Phase 2
Role of Estrogen on Skeletal Outcomes in FHA
Bone DensityFHA (Functional Hypothalamic Amenorrhea)Bone Strength
University of Virginia150 enrolled2 locationsNCT07010146
Recruiting
Phase 2
Testing Lutetium Lu 177 Dotatate in Patients With Somatostatin Receptor Positive Advanced Bronchial Neuroendocrine Tumors
Lung Neuroendocrine NeoplasmAdvanced Lung Neuroendocrine TumorFunctioning Lung Neuroendocrine Tumor+9 more
National Cancer Institute (NCI)70 enrolled29 locationsNCT04665739
Recruiting
Phase 2
Effect of Ketone Esters on Liver Fat Content and Metabolic Function
ObesityOverweight (BMI > 25)MASLD - Metabolic Dysfunction-Associated Steatotic Liver Disease
Washington University School of Medicine40 enrolled1 locationNCT07097506
Recruiting
Phase 2
A Study to Investigate Mibavademab in Adult Women With Functional Hypothalamic Amenorrhea
Functional Hypothalamic Amenorrhea (FHA)
Regeneron Pharmaceuticals34 enrolled10 locationsNCT07235917
Recruiting
Phase 2Phase 3
Efficacy, Safety, and Pharmacokinetics of Vericiguat in Pediatric Participants With Heart Failure Due to Left Ventricular Systolic Dysfunction (MK-1242-036)
Heart FailureLeft Ventricular Systolic Dysfunction
Merck Sharp & Dohme LLC342 enrolled107 locationsNCT05714085
Recruiting
Phase 1Phase 2
Stem Cells for Erectile Dysfunction Post RALP
Prostate CancerErectile Dysfunction
The Methodist Hospital Research Institute40 enrolled1 locationNCT07048314
Recruiting
Phase 2
A Precision Medicine Approach Using Gene Silencing to Treat a Chronic Liver Disease Called Metabolic Dysfunction-Associated Steatohepatitis (MASH) in Adult Participants at Increased Genetic Risk for This Condition
Metabolic dysfunction-associated steatohepatitis (MASH)
Regeneron Pharmaceuticals120 enrolled71 locationsNCT05519475
Recruiting
Phase 1Phase 2
A Study to Evaluate ALN-CIDEB in Adult Participants With Metabolic Dysfunction-Associated Steatotic Liver Disease or With Metabolic Dysfunction-Associated Steatohepatitis (MASLD/MASH)
Metabolic Dysfunction-Associated Steatotic Liver DiseaseMetabolic Dysfunction-Associated Steatohepatitis
Regeneron Pharmaceuticals132 enrolled4 locationsNCT06836609
Recruiting
Phase 2
A Study of Efimosfermin Alfa in Participants With Biopsy-confirmed Cirrhosis (Compensated) Due to MASH
Non-Alcoholic Fatty Liver DiseaseMetabolic Dysfunction-Associated Steatohepatitis
GlaxoSmithKline42 enrolled30 locationsNCT06920043
Recruiting
Phase 1Phase 2
Treating Heart Dysfunction Related to Cancer Therapy With Sacubitril/Valsartan
Heart FailureHeart Dysfunction
Virginia Commonwealth University70 enrolled1 locationNCT05194111
Recruiting
Phase 2Phase 3
Onabotulinum Toxin A (Botox) in the Treatment of Pharyngo-esophageal Dysphagia
Oropharyngeal DysphagiaTransfer DysphagiaCricopharyngeus Muscle Dysfunction
All India Institute of Medical Sciences100 enrolled1 locationNCT04695600
Recruiting
Phase 2
Ongoing Lung Decline With Age Intensified Response
Age-Related Lung Function Decline
Cedars-Sinai Medical Center40 enrolled1 locationNCT07676435
Recruiting
Phase 2
A Phase 2a Study of ALN-PNP With and Without a GLP1R Agonist in Adult Patients With Homozygous PNPLA3-Related MASLD
Metabolic dysfunction–associated steatotic liver disease (MASLD)
Regeneron Pharmaceuticals204 enrolled5 locationsNCT07527910
Recruiting
Phase 2
Inhaled Milrinone and Epoprostenol for the Prevention of Difficult Cardiac Pulmonary Bypass Separation
Right Ventricular DysfunctionRight Heart Failure
Montreal Heart Institute141 enrolled1 locationNCT05450328
Recruiting
Phase 2
Study to Evaluate Resmetirom in Post-Liver Transplant Patients With MASH
MASH - Metabolic Dysfunction-Associated Steatohepatitis
Madrigal Pharmaceuticals, Inc.120 enrolled17 locationsNCT07335601
Recruiting
Phase 2
UCSD Image-Guided Cognitive-Sparing Radiosurgery for Brain Metastases
CancerBrain Metastases, AdultNeurocognitive Function
Jona Hattangadi-Gluth60 enrolled1 locationNCT04343157
Recruiting
Phase 2
Safety and Efficacy of Crofelemer in Adult Patients With Short Bowel Syndrome and Intestinal Failure (SBS-IF) Without Colon-in-continuity (CIC)
Short Bowel SyndromeFunctional Gastrointestinal DisordersPost-Op Complication+2 more
Napo Therapeutics, S.p.A.18 enrolled8 locationsNCT06904872
Recruiting
Phase 2
Equol and Vascular Function in Women With Chronic Kidney Disease
Cerebrovascular functionBlood PressureCognitive Functions+2 more
University of Colorado, Denver74 enrolled1 locationNCT07194590