Gene Mutation Clinical Trials in Philadelphia, Pennsylvania

10 recruitingPhiladelphia, Pennsylvania

Showing 110 of 10 trials

Recruiting
Phase 2

Vismodegib, FAK Inhibitor GSK2256098, Capivasertib, and Abemaciclib in Treating Patients With Progressive Meningiomas

Intracranial MeningiomaRecurrent MeningiomaNF2 Gene Mutation
Alliance for Clinical Trials in Oncology124 enrolled781 locationsNCT02523014
Recruiting
Not Applicable

TUBectomy With Delayed Oophorectomy in High Risk Women to Assess the Safety of Prevention

Ovarian CancerBRCA1 Gene MutationBRCA2 Gene Mutation+3 more
University Medical Center Nijmegen3,000 enrolled66 locationsNCT04294927
Recruiting
Phase 1

A Study to Investigate the Safety and Tolerability of Ziftomenib in Combination With Venetoclax/Azacitidine, Venetoclax, 7+3, or 7+3+Quizartinib in Patients With AML

Acute Myeloid LeukemiaMyeloid SarcomaAcute Myeloid Leukemia, in Relapse+7 more
Kura Oncology, Inc.420 enrolled44 locationsNCT05735184
Recruiting

CTNNA1 Familial Expansion Study

Breast CancerGastric CancerCancer Gene Mutation
Abramson Cancer Center at Penn Medicine100 enrolled1 locationNCT05126290
Recruiting
Phase 2

A Study of Pembrolizumab With Trastuzumab and Chemotherapy in People With Esophagogastric Cancer

Esophageal CancerGastric AdenocarcinomaHER2 Gene Mutation
Memorial Sloan Kettering Cancer Center49 enrolled10 locationsNCT06123338
Recruiting
Phase 1

Neratinib and Fam-Trastuzumab Deruxtecan in Advanced Gastro-esophageal Cancer Patients

Gastric CancerGastrointestinal CancerHER2 Gene Mutation
Fox Chase Cancer Center18 enrolled3 locationsNCT05274048
Recruiting

The Myelin Disorders Biorepository Project

AdrenoleukodystrophyCockayne SyndromeRefsum Disease+63 more
Children's Hospital of Philadelphia12,000 enrolled23 locationsNCT03047369
Recruiting
Phase 3

The Cancer of the Pancreas Screening-5 CAPS5)Study

Pancreas CancerPeutz-Jeghers Syndrome (PJS)Gene Mutation+2 more
Johns Hopkins University9,000 enrolled9 locationsNCT02000089
Recruiting

ARTFL LEFFTDS Longitudinal Frontotemporal Lobar Degeneration (ALLFTD)

Amyotrophic Lateral SclerosisCorticobasal Degeneration (CBD)Progressive Supranuclear Palsy (PSP)+11 more
Mayo Clinic2,100 enrolled27 locationsNCT04363684
Recruiting
Phase 1Phase 2

Study of LP-184 in Patients With Advanced Solid Tumors

Advanced Solid TumorMetastatic Solid TumorTNBC - Triple-Negative Breast Cancer+4 more
Lantern Pharma Inc.175 enrolled9 locationsNCT05933265