Phase 1 Genetic Clinical Trials
12 recruitingPhase 1
What is a Phase 1 trial?
Phase 1 trials test a new treatment in a small group of people for the first time. The primary goal is to evaluate safety, determine a safe dosage range, and identify side effects. These studies typically enroll 20 to 80 participants.
Showing 1–12 of 12 trials
Recruiting
Phase 1Phase 2
Study of EPI-001 in Patients With Androgenetic Alopecia
androgenetic alopecia
Epibiotech42 enrolled1 locationNCT07618195
Recruiting
Phase 1Phase 2
Study of ABS-201 Evaluating Single and Multiple Ascending Doses in Healthy Adults With and Without Androgenetic Alopecia
Androgenetic alopecia (AGA)Healthy Volunteers - Male and Female
Absci Pty Ltd.227 enrolled4 locationsNCT07317544
Recruiting
Phase 1
Assessment of Topical Minoxidil on Intraoperative Flap Perfusion and Cutaneous Flap Viability in Breast Recon
Breast ReconstructionGenetic PredispositionPerfusion; Complications+1 more
Duke University25 enrolled1 locationNCT07264790
Recruiting
Phase 1Phase 2
A Study to Evaluate Safety and Efficacy of OLX72021 in Healthy Males With Androgenetic Alopecia
Androgenetic alopecia (AGA)
Olix Pharmaceuticals, Inc.158 enrolled1 locationNCT07327359
Recruiting
Phase 1Phase 2
Secretome vs. PRP Injections for Hair Density and Growth in Androgenetic Alopecia Patients
androgenetic alopecia
PT. Prodia Stem Cell Indonesia40 enrolled1 locationNCT07429253
Not Yet Recruiting
Phase 1
A study to assess the safety of increasing single doses of AP003 in healthy adults.
Liver-associated inborn errors of metabolismArg-TGA premature termination codon mutationsLiver stop codon disease+1 more
Alltrna, Incorporated30 enrolled1 locationACTRN12626000194369
Recruiting
Phase 1
Ketogenic Diet for Prevention of Epileptic Spasms in Infantile Onset Genetic Epilepsies
Genetic epilepsyDevelopmental and Epileptic EncephalopathiesEpileptic Spasms+1 more
Heather Olson10 enrolled1 locationNCT06700811
Recruiting
Phase 1Phase 2
Autologous Transplantation Combined With BCMA CAR-T in the Treatment of UHR-MM
Plasma Cell LeukemiaUltra High Risk mm (uhr-mm), 18-70 Years Old, Suitable for ASCT. And Meet Any of the Following uhr-mm DefinitionsCytogenetics Ultra High Risk+4 more
Institute of Hematology & Blood Diseases Hospital, China50 enrolled1 locationNCT07109323
Recruiting
Phase 1Phase 2
A Study of an FGFR2/3 Inhibitor (CGT4859) in Patients With Cholangiocarcinoma and Other Advanced Solid Tumors
CholangiocarcinomaAdvanced Solid TumorsIntrahepatic Cholangiocarcinoma (Icc)+9 more
Cogent Biosciences, Inc.110 enrolled15 locationsNCT06777316
Recruiting
Phase 1
Pharmacogenomic Contributions to Trihexyphenidyl Biotransformation and Response in Children With Dystonic Cerebral Palsy
Genetic PredispositionDystoniaPediatric Disorder+5 more
Children's Mercy Hospital Kansas City40 enrolled1 locationNCT06554288
Recruiting
Phase 1
Clinical Study of C402-CD19-CAR Treatment in Subjects With Relapsed or Refractory B-cell Lymphoma
Diffuse Large B Cell LymphomaDLBCL, Nos Genetic SubtypesFollicular Lymphoma Grade 3B+3 more
Shanghai Exuma Biotechnology Ltd.18 enrolled1 locationNCT06830031
Completed
Phase 1
A single-center study of the safety, tolerability and pharmacokinetics of a single concentration of topical SM04554 (0.25% concentration) solution in male subjects with androgenetic alopecia.
Androgenetic alopecia (AGA)
Samumed Pacific Pty Ltd25 enrolled1 locationACTRN12615000980538