Phase 1 HD Clinical Trials
15 recruitingPhase 1
What is a Phase 1 trial?
Phase 1 trials test a new treatment in a small group of people for the first time. The primary goal is to evaluate safety, determine a safe dosage range, and identify side effects. These studies typically enroll 20 to 80 participants.
Showing 1–15 of 15 trials
Recruiting
Phase 1
Methylphenidate to Address Attention and Executive Deficits Among Children With Sickle Cell Disease
Cognitive ImpairmentSickle Cell DiseaseAttention Deficit Hyperactivity Disorder (ADHD)+1 more
St. Jude Children's Research Hospital72 enrolled1 locationNCT07226219
Recruiting
Phase 1Phase 2
Prebiotic Galacto-oligosaccharide and Acute GVHD
Acute GVHD
University of Kansas Medical Center128 enrolled2 locationsNCT04373057
Recruiting
Phase 1
A Trial to Assess How Centanafadine Interacts With Stimulants in the Body
ADHD
Otsuka Pharmaceutical Development & Commercialization, Inc.42 enrolled1 locationNCT07314333
Recruiting
Phase 1
Safety and Preliminary Efficacy of ULSC in Facioscapulohumeral Muscular Dystrophy (FSHD)
FSHD - Facioscapulohumeral Muscular Dystrophy
Restem, LLC.16 enrolled1 locationNCT07086521
Recruiting
Phase 1Phase 2
ACTION: Trial of Adding Buprenorphine, CBT, and TMS to Improve Outcomes of Long-Term Opioid Therapy for Chronic Pain
Chronic PainOpioid Withdrawal
Medical University of South Carolina240 enrolled1 locationNCT06442566
Recruiting
Phase 1Phase 2
Overcoming Nicotine Dependence to Enable Quitting
Smoking CessationSmoking BehaviorsNicotine Dependence+2 more
Rush University Medical Center780 enrolled1 locationNCT05513872
Recruiting
Phase 1Phase 2
Dual-target iTBS for Youth With ADHD
ADHD
Shanghai Mental Health Center15 enrolled1 locationNCT07084649
Recruiting
Phase 1
Prevention of GvHD in Participants With Hematological Malignancies Undergoing Hematopoietic Stem Cell Transplant (HSCT)
Hematologic MalignancyGvHDGVHD,Acute+8 more
Tr1X, Inc.36 enrolled5 locationsNCT06462365
Completed
Phase 1
A Study to Evaluate the Safety, Tolerability, Pharmacokinetics, and Antiviral Activity of BJT-778 in Healthy Volunteers.
Chronic Hepatitis D Virus (HDV) InfectionChronic Hepatitis B Virus (HBV) Infection
Bluejay Therapeutics Inc32 enrolled1 locationACTRN12623000075684
Completed
Phase 1
A Study to Evaluate the Safety, Tolerability, Pharmacokinetics and Pharmacodynamics of NJA-730 in Healthy Volunteers
Acute graft-versus-host disease (aGvHD)
NapaJen Pharma Inc.104 enrolled1 locationACTRN12618001428257
Completed
Phase 1
A Dose-Escalation Safety Study of Yindan Softgels in Healthy Subjects
ischemic stroke sequelaeunstable angina pectoris of coronary heart disease (CHD)
Axeon Research (Au) Pty Ltd.40 enrolled1 locationACTRN12618000582257
Completed
Phase 1
Evaluation of the Pharmacokinetics of IPX233 Formulations in Healthy Volunteers
Attention Deficit Hyperactivity Disorder (ADHD)
Impax Pharmaceuticals,A Division of Impax Laboratories, Inc.20 enrolled1 locationACTRN12613001073796
Completed
Phase 1
Noribogaine Therapy for Relief of Opioid withdrawal, Phase 1B
Symptoms of opioid withdrawal
DemeRx Inc27 enrolled1 locationACTRN12613001064796
Not Yet Recruiting
Phase 1
Pharmacokinetics and Safety of Solid Oral Posaconazole(SCH 56592) in Subjects at High Risk for Invasive Fungal Infections
High Risk for Invasive Fungal Infection due to:
- Hematopoietic stem cell transplant (HSCT) recipients undergoing treatment for graft-versus-host disease (GVHD)High Risk for Invasive Fungal Infection due to:
- Expected neutropenia (low white blood cell count) due to chemotherapy for Acute Myelogenous Leukaemia (AML) or Myelodysplastic Syndrome (MDS)
Schering-Plough Pty limited160 enrolled1 locationACTRN12611000364976
Completed
Phase 1
To determine whether a pharmacokinetic drug-drug interaction occurs between atorvastatin and elinogrel.
chronic coronary heart disease (CHD)
Novartis Pharmaceutical Pty Limited28 enrolled1 locationACTRN12611000315910