Phase 1 ILD Clinical Trials
111 recruitingPhase 1
What is a Phase 1 trial?
Phase 1 trials test a new treatment in a small group of people for the first time. The primary goal is to evaluate safety, determine a safe dosage range, and identify side effects. These studies typically enroll 20 to 80 participants.
Showing 1–20 of 111 trials
Recruiting
Phase 1Phase 2
Novel Indenoisoquinolone CMYC/TOPOISOMERASE 1 Inhibitor (LMP744) in Recurrent Glioblastoma
Brain CancerGBMGlioma+12 more
National Institute of Neurological Disorders and Stroke (NINDS)40 enrolled1 locationNCT07416188
Recruiting
Phase 1
PET Imaging of Phosphodiesterase-4 (PDE4) in Volunteers With Alzheimer Disease (AD) or Mild Cognitive Impairment (MCI)
HealthyMild Cognitive ImpairmentAlzheimer s Disease
National Institute of Mental Health (NIMH)90 enrolled1 locationNCT07169630
Recruiting
Phase 1
PET Imaging of Cyclooxygenases in Neurodegenerative Brain Disease
DementiaALSMild Cognitive Impairment+2 more
National Institute of Mental Health (NIMH)184 enrolled1 locationNCT04396873
Recruiting
Phase 1
Immunotherapy for Malignant Pediatric Brain Tumors Employing Adoptive Cellular Therapy (IMPACT)
PineoblastomaEmbryonal Tumor With Multilayered RosettesEpendymoma+3 more
Children's National Research Institute12 enrolled1 locationNCT06193759
Recruiting
Phase 1Phase 2
A Study of Debio 0123 in Combination With Temozolomide in Adult Participants With Recurrent or Progressive Glioblastoma and of Debio 0123 in Combination With Temozolomide and Radiotherapy in Adult Participants With Newly Diagnosed Glioblastoma
Glioblastoma IDH (Isocitrate Dehydrogenase) WildtypeAstrocytoma, Grade III
Debiopharm International SA116 enrolled16 locationsNCT05765812
Recruiting
Phase 1
Testing the Addition of an Anti-Cancer Drug, Triapine, to the Usual Radiation Therapy for Recurrent Glioblastoma or Astrocytoma
Astrocytoma, IDH-Mutant, Grade 2Recurrent Adult Diffuse Hemispheric Glioma, H3 G34-MutantRecurrent Adult Diffuse Midline Glioma, H3 K27-Mutant+4 more
National Cancer Institute (NCI)30 enrolled42 locationsNCT06860594
Recruiting
Phase 1
R-3750 in Patients With Mild to Moderate Ulcerative Colitis
Ulcerative ColitisUlcerative Colitis ChronicUlcerative Colitis Chronic Mild+1 more
Rise Therapeutics LLC36 enrolled5 locationsNCT05666960
Recruiting
Phase 1
Locoregional Administration of Genetically Engineered Cells (EGFR/IL13Rα2 Pool-CAR T Cells) for the Treatment of Recurrent or Progressive High-Grade Gliomas
Recurrent Astrocytoma, IDH-Mutant, Grade 4Recurrent Glioblastoma, IDH-Wildtype
City of Hope Medical Center24 enrolled1 locationNCT07544992
Recruiting
Phase 1Phase 2
CANnabinoids in Pediatric ONCology
CancerChildhood Cancer
University of Manitoba60 enrolled3 locationsNCT05754840
Recruiting
Phase 1
A Study of CDX-622 in Participants With Mild to Moderate Asthma
Mild to Moderate Asthma
Celldex Therapeutics12 enrolled4 locationsNCT07330778
Recruiting
Phase 1
A Study of 177Lu-PSMA-617 in People With Gliomas
GliomaGlioblastoma, IDH-wildtypeDiffuse Midline Glioma, H3 K27-Altered+3 more
Memorial Sloan Kettering Cancer Center20 enrolled7 locationsNCT07223034
Recruiting
Phase 1
A Phase I Study in Healthy Volunteers and Parkinson's Disease (PD) Patients.
Early-stage Parkinson’s diseaseParkinson's Disease (PD)Mild to Moderate Parkinson's Disease
Mission Therapeutics106 enrolled5 locationsNCT07630545
Recruiting
Phase 1
Tegavivint With Gemcitabine in Patients With Relapsed or Refractory Osteosarcoma
Refractory OsteosarcomaOsteosarcoma in ChildrenOsteosarcoma Recurrent+1 more
Emory University24 enrolled1 locationNCT07144254
Recruiting
Phase 1
Safety And Tolerability Of Gamma Glutamylcysteine (GGC) Oral Supplementation In MCI Patients
Mild Cognitive Impairment (MCI)
Pravat Mandal9 enrolled1 locationNCT07583251
Recruiting
Phase 1
Genetically Engineered Cells (Anti-CD19/CD20/CD22 CAR T-cells) for the Treatment of Relapsed or Refractory Lymphoid Malignancies
Recurrent Chronic Lymphocytic LeukemiaRefractory Chronic Lymphocytic LeukemiaRecurrent Non-Hodgkin Lymphoma+15 more
Sumithira Vasu54 enrolled2 locationsNCT05418088
Recruiting
Phase 1Phase 2
Haemodynamic Effects of Dobutamine in Patients With Wild-type Transthyretin Amyloid Cardiomyopathy (ATTRwt)
ATTR Amyloidosis Wild Type
Steen Hvitfeldt Poulsen15 enrolled1 locationNCT06318260
Recruiting
Phase 1Phase 2
Combination of Tarlatamab and Temozolomide in Patients With Central Nervous System Tumors
GliomaCNS Tumor, AdultCNS Tumor, Childhood
Centre Leon Berard70 enrolled12 locationsNCT07243470
Recruiting
Phase 1Phase 2
CNP-103 in Adolescent and Adult Subjects Ages 12-35 With Recently Diagnosed (Within 6 Months) Stage 3 Type 1 Diabetes (T1D)
Type 1 DiabetesType 1 Diabetes MellitusType 1 Diabetes Mellitis+7 more
COUR Pharmaceutical Development Company, Inc.72 enrolled30 locationsNCT06783309
Recruiting
Phase 1
TREAD: Time Restricted Eating Intervention for Alzheimer's Disease
Alzheimer DiseaseMild Cognitive ImpairmentAlzheimer s Disease
University of California, San Diego60 enrolled1 locationNCT06548191
Not Yet Recruiting
Phase 1
A trial to assess the safety, tolerability and efficacy of RES-010 in overweight and obese adults without obesity-related comorbidities.
OverweightObesity (Mild)
Resalis Therapeutics Australia Pty Ltd36 enrolled1 locationACTRN12626000615381