Phase 2 Immune Clinical Trials
143 recruitingPhase 2
What is a Phase 2 trial?
Phase 2 trials evaluate whether a treatment works for a specific condition and further assess its safety. These studies typically enroll several hundred participants and provide preliminary data on effectiveness.
Showing 1–20 of 143 trials
Recruiting
Phase 2
Rituximab Plus Cyclosporine in Idiopathic Membranous Nephropathy
Autoimmune DiseaseProteinuriaGlomerular Disease+2 more
National Institute of Diabetes and Digestive and Kidney Diseases (NIDDK)30 enrolled2 locationsNCT00977977
Recruiting
Phase 2Phase 3
RESET-Myositis: An Open-Label Study to Evaluate the Safety and Efficacy of CABA-201 in Subjects With Active Idiopathic Inflammatory Myopathy or Juvenile Idiopathic Inflammatory Myopathy
DermatomyositisIdiopathic Inflammatory MyopathyAnti-synthetase Syndrome+5 more
Cabaletta Bio74 enrolled35 locationsNCT06154252
Recruiting
Phase 2
Allogeneic Hematopoietic Cell Transplantation for Peripheral T Cell Lymphoma
Lymphoproliferative DisordersImmune System DiseasesPeripheral T-cell Lymphomas
National Cancer Institute (NCI)330 enrolled2 locationsNCT03922724
Recruiting
Phase 1Phase 2
Safety and Preliminary Efficacy of CTX112 in Adult Participants With Relapsed/Refractory Hematologic Autoimmune Disease
Immune Thrombocytopenic PurpuraITP - Immune ThrombocytopeniaWarm Autoimmune Hemolytic Anemia+1 more
CRISPR Therapeutics AG60 enrolled8 locationsNCT07549698
Recruiting
Phase 2
Study of Ianalumab in Adults With Primary Immune Thrombocytopenia (ITP) and Warm-antibody Autoimmune Hemolytic Anemia (wAIHA) Who Have Previously Benefited From Ianalumab
Warm Autoimmune Hemolytic AnemiaPrimary immune thrombocytopenia
Novartis Pharmaceuticals60 enrolled25 locationsNCT07039422
Recruiting
Phase 2
SG301-SC Injection Safety Study in Subjects With Primary ITP Patients
Primary immune thrombocytopenia
Hangzhou Sumgen Biotech Co., Ltd.60 enrolled5 locationsNCT07710248
Recruiting
Phase 2
A Study to Assess the Tolerability of Ianalumab (VAY736) With Investigator's Choice Thrombopoietin Receptor Agonist (IC TPO-RA) in Patients With Primary Immune Thrombocytopenia (ITP)
Primary Immune Thrombocytopenia (ITP)Primary Evans Syndrome (ES)
Novartis Pharmaceuticals164 enrolled5 locationsNCT07421167
Recruiting
Phase 2
METabolic MODulation to Enhance Insulin Sensitivity and Mitochondrial Function in Type 1 Diabetes (MetMod-T1D)
Endocrine System DiseasesImmune System DiseasesAutoimmune Diseases+6 more
University of Washington60 enrolled2 locationsNCT07699380
Recruiting
Phase 2Phase 3
A Study of Efgartigimod IV in Participants From 12 Years to Less Than 18 Years of Age With Chronic Immune Thrombocytopenia (ITP)
Immune Thrombocytopenic PurpuraITPIdiopathic Thrombocytopenic Purpura+4 more
argenx24 enrolled20 locationsNCT07194850
Recruiting
Phase 2
Study to Assess the Safety and Tolerability of Tafasitamab in Adult Participants With Primary Autoimmune Blood Cell Disorders
Immune Thrombocytopenia
Incyte Corporation56 enrolled40 locationsNCT07104565
Recruiting
Phase 2
TCR Alpha Beta T-cell Depleted Haploidentical HCT in the Treatment of Primary Immunodeficiency and Inherited Metabolic Disorders in Children
Metabolic DiseasePrimary Immune Deficiency Disorders
Johns Hopkins All Children's Hospital17 enrolled1 locationNCT04414046
Recruiting
Phase 1Phase 2
Controlling Hyperactive Immunity With Long-lived Lymphocytes
Rheumatoid Arthritis (RA)Autoimmune Rheumatologic DiseaseDiffuse Cutaneous Systemic Sclerosis+1 more
Quell Therapeutics Limited16 enrolled6 locationsNCT07473154
Recruiting
Phase 2
Pilot Trial of Allogeneic Blood or Marrow Transplantation for Primary Immunodeficiencies
Lymphoproliferative DisordersImmune System DiseasesCommon Variable Immunodeficiency+2 more
National Cancer Institute (NCI)354 enrolled2 locationsNCT02579967
Recruiting
Phase 1Phase 2
A Study of Pirtobrutinib in Participants With Immune Thrombocytopenia
Immune Thrombocytopenia (ITP)
Eli Lilly and Company68 enrolled45 locationsNCT06721013
Recruiting
Phase 1Phase 2
Autoimmune Disease Treatment With Mesenchymal Stem Cells (MSCs) and CAR-T Cells
Autoimmune Diseases
Shenzhen Geno-Immune Medical Institute30 enrolled1 locationNCT06435897
Recruiting
Phase 2
Evaluate the Efficacy and Safety of Ruxolitinib on Hair Regrowth in Patients With Autoimmune Polyendocrinopathy Candidiasis Ectodermal Dystrophy (APECED)-Associated Alopecia Areata
Alopecia AreataAutoimmune Polyendocrinopathy Candidiasis Ectodermal Dystrophy (Apeced)
National Institute of Allergy and Infectious Diseases (NIAID)70 enrolled1 locationNCT05398809
Recruiting
Phase 1Phase 2
CAR-T Cells Targeting Autoimmune Diseases
Autoimmune Diseases
Shenzhen Geno-Immune Medical Institute30 enrolled1 locationNCT05459870
Recruiting
Phase 2
Intestinal Low-Dose Radiotherapy Plus Immunochemotherapy for Conversion of Borderline Resectable/Unresectable Esophageal Squamous Cell Carcinoma
ChemotherapyRadiotherapyImmune Checkpoint Inhibitor+4 more
Chuangzhen Chen43 enrolled1 locationNCT07339488
Recruiting
Phase 2Phase 3
Sirolimus in Patients With Systemic Lupus Erythematosus-Associated Immune Thrombocytopenia
Systemic Lupus ErythematosusImmune Thrombocytopenia
Chinese SLE Treatment And Research Group164 enrolled1 locationNCT07657793
Recruiting
Phase 2
Orelabrutinib in the Treatment of Relapsed/Refractory AIHA
Autoimmune Hemolytic Anemia, AIHA
Peking Union Medical College Hospital50 enrolled1 locationNCT07453368